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Fig 1 - Placental Transport in Response to Altered Maternal Nutrition

The placental barrier in the human term placenta. The figure represents a cross-section of the human placenta. The insert to the right shows a schematic illustration of the placental barrier, which at term mainly consists of the syncytiotrophoblast (ST) cell and the fetal capillary (FC) endothelial cell. Of these structures, it is primarily the two polarized syncytiotrophoblast plasma membranes, the microvillous plasma membrane (MVM) and the basal plasma membrane (BPM) that restrict the transfer of molecules like ions and amino acids. N, nucleus of syncytiotrophoblast cell; IVS, intervillous space; SA, spiral artery; VT, villous tree; UC, umbilical cord. Reproduced by permission from Elsevier Ltd.
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