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- Analysis of iris surface features in populations of diverse ancestry

The five features found most commonly in the human iris. The arrows are pointing to the features in images b, c and e. Fuchs’ crypts (a) are lacunae in the anterior border of the iris which arise during resorption of the pupillary membrane. They may be either large or small and closely resemble windows. Four sample crypts are outlined in the image above. Wolfflin nodules (b) are small bundles of collagen that are the consequence of atrophy in the stromal layer of the iris. Pigment spots (c) are discrete areas of pigmentation that can be observed on the surface of the iris. Spots that distort the stromal layer are referred to as nevi and spots that do not distort the stromal layer are referred to as freckles. Contraction furrows (d) are rings that extend around the outer border of the iris. They closely resemble wrinkles and are the product of the contraction and dilation of the pupil. Furrows are typically discontinuous and staggered across the iris. In the above image, the black line follows the path of the furrows around the eye. Conjunctival melanosis (e) is spotting that can be observed on the scleral region surrounding the iris. It is usually benign, and is found more commonly in some ancestries than in others.
The five features found most commonly in the human iris. The arrows are pointing to the features in images b, c and e. Fuchs’ crypts (a) are lacunae in the anterior border of the iris which arise during resorption of the pupillary membrane. They may be either large or small and closely resemble windows. Four sample crypts are outlined in the image above. Wolfflin nodules (b) are small bundles of collagen that are the consequence of atrophy in the stromal layer of the iris. Pigment spots (c) are discrete areas of pigmentation that can be observed on the surface of the iris. Spots that distort the stromal layer are referred to as nevi and spots that do not distort the stromal layer are referred to as freckles. Contraction furrows (d) are rings that extend around the outer border of the iris. They closely resemble wrinkles and are the product of the contraction and dilation of the pupil. Furrows are typically discontinuous and staggered across the iris. In the above image, the black line follows the path of the furrows around the eye. Conjunctival melanosis (e) is spotting that can be observed on the scleral region surrounding the iris. It is usually benign, and is found more commonly in some ancestries than in others.
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