The chromosome distribution and synteny analysis of SjERFs. (A) Chromosomal locations and their synteny of SjERFs. The connecting lines indicate duplicated gene pairs in 59 SjERFs. (B) The phylogenetic tree of SjERFs and functional ERF cluster. (C) The topologically associating domains (TADs) region of three SjERFs.

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Phylogenetic tree of 59 SjERFs and 121 AtERFs. The ERF protein...

Schematic diagram of phylogenetic analysis, exon/intron distribution,...

Pivotal cis−elements in the promoter of SjERF TFs.

The chromosome distribution and synteny analysis of SjERFs. (A)...

Members of the SjERFs cluster specifically bind to the GCC boxes in the...

Genome-wide analysis of the ERF Family in Stephania japonica provides insights into the regulatory role in Cepharanthine biosynthesis

Article

Full-text available

Sep 2024

Hanting Yang
Baimei Liu
Haiyan Ding
[...]
Chi Song

Introduction Cepharanthine (CEP), a bisbenzylisoquinoline alkaloid (bisBIA) extracted from Stephania japonica, has received significant attention for its anti-coronavirus properties. While ethylene response factors (ERFs) have been reported to regulate the biosynthesis of various alkaloids, their role in regulating CEP biosynthesis remains unexplor...