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Tephrosia purpurea. 

Tephrosia purpurea. 

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Tephrosia purpurea is a wild herb belongs to the family fabaceae and commonly known as sharpunkha. It is distributed among India, Australia, China, Sri Lanka up to 400 m to 1300 m altitude. It occurs naturally in the waste places along the road sides and it prefers to grow in dry, gravelly or rocky and sandy soil. It is being used as folk medicine...

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... Modern pharmacological studies have shown that the plant has wound healing, antileishmanial, anticarcinogenic, antimicrobial, antioxidant, hepatoprotective, antifertility, antispermatogenic, anti-diarrheal, diuretic, and insecticidal properties. Acetylcholinesterase inhibitory action reported from this plant aids its utilization for the development of drugs for Alzheimer's and dementia neurological disorders (Alam, 2004;Kumar et al., 2012;Bathini et al., 2012;Arriaga et al., 2014;Anbarasi and Vidhya, 2015;Arjun et al., 2016;Babu et al., 2017;Rao et al., 2020). Tephrosia purpurea is commonly known as Bano Kuthi. ...
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Tephrosia purpurea is a common plant in India and is treated as a weed. It is commonly grown near roadsides and wastelands. It has ethnomedicinal uses, but nowadays people ignore it. Keeping this in mind, an attempt has been made to document the bioactive compounds available in the leaves through phytochemical screening. Results showed the presence of saponin, flavonoids, tannin, phenolic compounds, and reducing sugar. The detected compounds could be responsible for the therapeutic values of T. purpurea leaves, bringing attention to the importance of roadside plants.
... The reduction method was used to prepare the Ag Nanoparticles suggested by Wen et al. [26]. ...
... The synthesized nanoparticles were purified by centrifugation at 15000rpm for 20 minutes and redispersed in deionized water. It was left for drying and dried powder was used for different analysis [26]. ...
... It was slightly gelly like which was vacuum filtered; the filtrate was dried and washed with distilled water uptil it was neutralized. It was dried in oven on upto 70 o C [26,27]. ...
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The research is focused on screening various bioactive extracts from Tephrosia purpurea plant leaf for the onward synthesis of nanomaterial and formation of Grephene-Ag nanocomposite for their biological applications. The aerial parts of this plant are comprised of primary and secondary metabolites. Its latex contains many important compounds such as Phenolics, Flavonides, and Terpenes, etc. Tephrosia purpurea is used as a traditional medicine to cure different problems of the digestive and respiratory tract. The aerial parts of this plant show immense antifungal and antimicrobial pursuits. Silver nanoparticles were synthesized from methanol extract of aerial parts of the Tephrosia Purpurea. These nanoparticles were reacted with lab synthesized Graphene to form Plant-Silver-Graphene nanocomposites. The characterization of plant extract, extract-mediated Ag-nanoparticles, and graphene-metal nanocomposites was carried out by different techniques like FTIR, UV, EDX & SEM. FTIR & UV spectra peaks were found in the ranges already reported. EDX analysis shows the percentage of the elements matching the reported data. SEM shows similar ranges of nanoparticle sizes as found in the research papers. Moreover, anticancer activities of plant-Ag-graphene nanocomposites were done & comparison was made with parent materials. The results were remarkable as plant-Ag-graphene nanocomposites showed better anticancer activities than the nanoparticles and plant extract.
... The increased number of bacteria with drug resistance creates a global problem for people. This scenario is so crucial that medicines become ineffective and pan-resistant bacteria spread enormously [2][3][4]. As bacterial species that are becoming resistant to different antibiotics increased the health care cost. ...
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AgNPs are employed in several applications, and we used Ipomoea carnea aqueous leaves extract to enhance the metal nanoparticle synthesis process. This study suggested that aqueous extract from I. carnea leaves can reduce silver nitrate (AgNO3) and act as a stabilizing and capping agent. The specific Plasmon resonance (SPR) was found between 390-410 nm in a UV–Vis spectrophotometer. “Field Emission Scanning Electron Microscope (FE-SEM)” and “X-ray diffraction (XRD)” analysis confirm the size between 11.21 nm to 46.90 nm with spherical face-center-cubic (FCC) crystals. Additionally, the antibacterial activity of synthesized AgNPs was also evaluated against four standard bacterial pathogens i.e. Klebsiella pneumoniae (MTCC 432), Staphylococcus aureus (MTCC 1144), Streptococcus pneumoniae (MTCC 655), and Pseudomonas aeruginosa (MTCC 2474) and Brine shrimp lethality assay (BSLA) was used to check the toxicity. Synthesized AgNPs were found significantly effective against all MTCC strains with a 1359.03 ng/mL LC50 value.
... Whole plant is utilized as laxative, dried part has diuretic properties whereas roots and seeds are utilized as vermifuge, insecticidal and skin eruption. For the treatment of vomiting its decoction is utilized and its pods extract effectively utilized during inflammation and pain (Deshpande et al., 2003;Babu et al., 2017). ...
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Medicinal plants have been necessary to conventional and non-customary types of prescriptions dating back to somewhere around 5000 years ago. Researchers progressively depend on current logical techniques and proof-based medication to demonstrate the viability of herbal medicines and spotlight on a better comprehension of the systems of their activity. Notwithstanding, data concerning quantitative human health advantages on natural remedies is yet uncommon, constraining their legitimate valuation. Traditional medicines are regularly utilized for the wound-healing process covering a wide zone of various skin-related infections. This chapter will give information about the wound-healing capability of plants that are useful for the advancement of new wound-healing formulations.
... Whole plant is utilized as laxative, dried part has diuretic properties whereas roots and seeds are utilized as vermifuge, insecticidal and skin eruption. For the treatment of vomiting its decoction is utilized and its pods extract effectively utilized during inflammation and pain (Deshpande et al., 2003;Babu et al., 2017). ...
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A vast majority of the world’s population lacks access to essential medicines and the provision of safe healthcare services. Medicinal plants and herbal medicines can be applied for pharmacognosy, or the discovery of new drugs, or as an aid for plant physiology studies. In recent years, there has been increased interest in the search for new chemical entities and the expression of resistance of many drugs available in the market has led to a shift in paradigm towards medicinal research. Herbal treatments, the most popular form of folk medicine, may become an important way of increasing access to healthcare services. Advanced Pharmacological Uses of Medicinal Plants and Natural Products provides emerging research exploring the theoretical and practical aspects of drug discovery from natural sources that allow for the effective treatment of human health problems without any side effects, toxicity, or drug resistance. Featuring coverage on a broad range of topics such as ethnobotany, therapeutic applications, and bioactive compounds, this book is ideally designed for pharmacologists, scientists, ethnobotanists, botanists, health researchers, professors, industry professionals, and health students in fields that include pharmaceutical drug development and discovery.
... It also occurs in wastelands along the roadsides. It prefers to grow in dry, gravelly or rocky and sandy soil (Babu, Singh, & Singh, 2017). A large number of Tephrosia species along with T. purpurea (L.) Pers. ...
... Pods extract has been reported to have analgesic and antiinflammatory potential, while their decoction being usefull in vomiting (Gokhale, Dikshit, Damre, Kulkarni, & Saraf, 2000). Roots are able to cure various skin disorders, elephantiasis, and flatulence (Babu et al., 2017); root juice is used in treating skin eruptions (Palbag et al., 2014), and root powder is used for brushing teeth and curing various dental problems like Gingivitis (Dalwadi et al., 2014). Inhalation of T. purpurea smoke has been documented as an excellent remedy for curing cough and cold. ...
Article
Tephrosia purpurea (L.) Pers. is a well‐known plant in Ayurveda and named “Sarwa wranvishapaka” for its property to heal wounds. Traditionally, it is practiced for impotency, asthma, dyspepsia, hemorrhoids, syphilis gonorrhea, rheumatism, enlargement of kidney and spleen. It is an important component of herbal preparations like Tephroli and Yakrifti used to cure liver disorders. Various phytocompounds including pongamol, purpurin, purpurenone, tephrosin, bulnesol, tephrostachin, β‐sitosterol, and so on have been reported. Modern pharmacological studies have shown that the plant have wound healing, antileishmanial, anticarcinogenic, antimicrobial, antioxidant, hepatoprotective, antifertility, antispermatogenic, anti‐diarrheal, diuretic, and insecticidal properties. Acetylcholinesterase inhibitory action reported from this plant aids its utilization for the development of drugs for Alzheimer's and dementia neurological disorders. Among the known active compounds of T. purpurea, tephrostachin is responsible for antiplasmodial activity, tephrosin, pongaglabol, and semiglabrin exerts antiulcer activity while quercetin, rutin, β‐sitosterol, and lupeol are mainly responsible for its anti‐inflammatory and anti‐cancer properties. From different toxicological studies, concentrations up to 2,000 mg/kg were considered safe. The present review comprehensively summarizes the ethnomedicine, phytochemistry, pharmacology, and toxicology of T. purpurea. Further research on elucidation of the structure–function relationship among active compounds, understanding of multi‐target network pharmacology and clinical applications will intensify its therapeutic potential.
... Whole plant is utilized as laxative, dried part has diuretic properties whereas roots and seeds are utilized as vermifuge, insecticidal and skin eruption. For the treatment of vomiting its decoction is utilized and its pods extract effectively utilized during inflammation and pain (Deshpande et al., 2003;Babu et al., 2017). ...
Chapter
Full-text available
Medicinal plants have been necessary to conventional and non-customary types of prescriptions dating back to somewhere around 5000 years ago. Researchers progressively depend on current logical techniques and proof-based medication to demonstrate the viability of herbal medicines and spotlight on a better comprehension of the systems of their activity. Notwithstanding, data concerning quantitative human health advantages on natural remedies is yet uncommon, constraining their legitimate valuation. Traditional medicines are regularly utilized for the wound-healing process covering a wide zone of various skin-related infections. This chapter will give information about the wound-healing capability of plants that are useful for the advancement of new wound-healing formulations.
Article
Tephrosia purpurea, which is also termed as sharpunkha in Ayurveda, is a wild herb of family Fabaceae. Geographically it is found at an altitude between 400 m to 1300 m in countries like India, Sri Lanka, China and Australia. Natural habitat of Tephrosia purpurea is in dry, sandy or rocky soil. It is seen growing along the roadside and places where waste are dump. Phytochemical investigations on Tephrosia purpurea shows the presence of constituents such as carbohydrates, protein, amino acid, tannins, saponins, terpenes, flavanones, rotenoids, chalcones, isoflavones, glycosides, alkaloids, flavanols, and sterols. It has also shown the presence of lupeol, lanceolatins A and B semiglabrin, rutin, sitosterol and pongamole. Flavonoids such as (+)-tephrosin A and B, (+)-tephrosone, isoflavone, 7, 4' dihydroxy-3', 5'-dimethoxyflavone and a chalcone, (+)-tephropurpurin were present in the whole plant and that was isolated from it. Different parts of the whole plant has shown variety of pharmacological actions ranging from anti-inflammatory to antitumor along with activities such as antiulcer , hepatoprotective, antioxidant, antimicrobial and antiallergic. Moreover it has also shown insect repellent activity. This review has summarized the literature related to phytochemical and pharmacological study of Tephrosia purpurea (L.) Pers. till August 2012. Tephrosia purpurea is regarded as folk medicine due to several therapeutic properties like anti-daibetic, anticancer, antipyretic. It also has pharmacological importance due to the potent chemical constituent.