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The aim of this study was to investigate the accuracy of widal test by compared with enzyme linked immunosorbent assay (ELISA) as standard method and for this purpose 150 blood samples were pulled from patients suspected infected with typhoid fever coming to Azadi Teaching Hospital and Children's Hospital in Kirkuk Governorate from 1-09-2016 to 1-1...
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Background
As physicians in a referral hospital, we observed the association between history of enteric fever and somatic disorders associated with low mood. At the Al-Hussein University Hospital, Cairo and the National Liver Institute Hospital, Menoufia, we receive patients from all over Egypt, including rural areas where enteric fever is endemic....
This study was conducted in Babylon governorate in the period from January 2019 to April 2019 .Patients were randomly selected from Al-Musayyib General Hospital and Marjan Medical city,aclinics and laboratories in the Musayyib of Babylon governorate for patients suspected of typhoid fever, according to the diagnosis of the specialist physician. 150...
Introduction: Enteric fever which includes typhoid and paratyphoid fever is a systemic febrile illness caused by the bacteria Salmonella enterica serovar typhi and Salmonella enterica serovar paratyphi A, B and C respectively. Although the gold standard for definitive diagnosis of Enteric fever is isolation of Salmonella species in culture, the Wid...
Background: Typhoid fever is a potentially fatal multisystemic illness caused primarily by Salmonella enterica (S enterica) subspecies enterica serovar typhi and, to a lesser extent, related serovars paratyphi A, B, and C and others. Objectives: Is to assess different methods in diagnosing typhoid fever in the patients attending Al-Kindy Teaching H...
Typhoid fever is a systemic infectious disease caused by Salmonella enteric serotype typhi. Laboratory tests are essential because the clinical symptoms of typhoid fever are not specific. The definitive diagnosis of typhoid fever make by culture isolation of Salmonella typhi, but this test is expensive and takes a long time. Other supporting tests...
Citations
... Furthermore, there were studies reporting higher positivity of the Widal test to be 100%, 84.7%, 72.58%, and 74%, as compared to our study. [2,[11][12][13] The rapid card test offers simplicity, speed, economy, and early diagnosis with high sensitivity and specificity. The detection of IgM antibodies suggests acute typhoid in the early phase of infection, while the detection of both IgG and IgM antibodies suggests acute typhoid in the middle phase of infection. ...
Background
Typhoid fever is a serious public health problem. It causes severe systemic infection in lesser developed areas of the world. Although blood culture is regarded as the gold standard for diagnosis, it is a time taking procedure. An early and accurate diagnosis is necessary for an effective treatment.
Aims
The present study was done to comparatively evaluate rapid card and Widal slide agglutination tests for rapid diagnosis of typhoid cases.
Settings and Design
The study design was a cross-sectional descriptive study done over a period of 6 months from January to June 2018.
Materials and Methods
A total of 265 patients suspected of typhoid fever who gave their consent were included in the study whose blood samples were tested by both rapid card and Widal slide agglutination tests.
Statistical Analysis Used
The collected data were analyzed using SPSS Data Editor Software version 20. Percentage of variables was calculated.
Results
Of 265 patients, 97 patients were positive by the Widal slide test, whereas 113 patients were positive by the rapid card test, with 96.9% sensitivity and 88.7% specificity. Of 113 positives, 83 cases were positive for immunoglobulin M (IgM) only, whereas 30 cases were positive for both IgM and IgG.
Conclusion
Rapid card test is a simple and easy to perform the diagnostic test for rapid detection of typhoid cases with an additional advantage of separate determination of IgM and IgG antibody, thereby aiding in identification of current infection and previous exposure so that appropriate and timely treatment could be given to the patients.
Enteric fever is an acute febrile disease caused by Salmonella typhi as well as Paratyphi (A, B, C). This study was carried out to determine how common the enteric fever Salmonellae is among patients presenting with fever in a tertiary hospital in Jos, Nigeria using culture and serological methods. A total of 132 samples (consisting of stool, blood, and serum) were collected from 44 patients presenting with fever. Stool and blood samples were used for culture while serum from blood was examined for the presence and levels of Salmonella antibodies by widal agglutination test using the rapid slide screening method and tube confirmatory test. The results of this study suggested that enteric fever is not a prevalent disease in Jos, Nigeria. Of the 44 sera tested, no significant Salmonella agglutinin titre was detected. Also, of the 44 blood and 44 stool specimens cultured no Salmonella typhi or paratyphi was isolated. This study detected titre values of Salmonella that were not significant diagnostically but normal in the population under consideration. In the diagnosis of enteric fever, it is suggested that the presumptive serological test (widal) be carried out along with cultures from blood and stool to avoid misdiagnosis and empirical treatment.
Enteric fever or typhoid fever is a life-threatening multi-system infection common in underdeveloped nations. Blood cultures give unequivocal proof of infection and are the cornerstone of laboratory diagnosis. RDTs detect IgM within 2-3 days after infection. IgM indicates a recent infection, while IgG indicates a distant infection. Study goal: To examine the role of serological tests as a first test while waiting for blood culture results and to demonstrate IgM and IgG accuracy in recognizing typhoid illness in children. Cross-sectional research with analytic component done at the Karbala Children's Teaching Hospital. The research included 81 children with typhoid-like symptoms, including fever, headache, vomiting, and stomach discomfort. The investigation yielded hematological, biochemical, and serological outcomes. A blood culture was performed to verify the diagnosis. Most study participants (78/96.3%) had positive anti-salmonella IgM findings, whereas 32/39.5% did. Blood cultures diagnosed 47 (58%) study individuals with typhoid fever (Salmonella infection). Positive blood cultures provide 43 (91.5%) ciprofloxacin-susceptible isolates. Anti-salmonella IgM has 95.7% sensitivity and 5.6% specificity. 70.8% anti-salmonella IgM accuracy. Anti-salmonella IgG had 38.3% sensitivity and 61.1% specificity. Anti-salmonella IgG had 44.6% accuracy. The major sign of enteric fever is a high body temperature, along with anorexia, vomiting, stomach discomfort, and headache. The main risk factor is water availability. Serological tests with a positive IgM result serve a significant role in diagnosing typhoid fever and commencing antibiotic treatment early while waiting for blood culture results.
