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... of various chlorides with piperidine derivatives such as 4-piperidone hydrochloride hydrate 13 or 1-Boc-4-piperidylmethanamine 15 yielded a series of five piperidine analog amides in satisfactory yields (Scheme 4; Table 2). The final structures of all the compounds synthesized have been established by the usual spectroscopic analyses, such as NMR and LC/MS, and the structures are in line with those expected. ...Similar publications
Superbugs are microorganisms that have evolved and developed the ability to resist antibiotics. The spread of these pathogens is a serious health problem, causing diseases that are difficult to treat. In addition to antimicrobial resistance, superbugs have several virulence factors that are essential for establishment and invasion during infections...
