Synthesis of 1,2,3‐triazolium iodides 5a and 5b having identical N‐1 and N‐3 substituents.

Synthesis of 1,2,3‐triazolium iodides 5a and 5b having identical N‐1 and N‐3 substituents.

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1,3,4‐Trisubstituted 1,2,3‐triazolium salts having either aliphatic or benzylic substituents at the N‐1 and N‐3 positions were synthesized in two steps involving: i) copper(I) catalyzed azide‐alkyne 1,3‐dipolar cycloaddition (CuAAC), and ii) N‐alkylation of the 1,2,3‐triazole intermediates. Trans‐N‐alkylation reactions in bulk and in the presence o...