Solvent switched synthesis of alkynyl and monofluoroalkenyl isoindolinones in MeOH and ⁱPrCN.

Solvent switched synthesis of alkynyl and monofluoroalkenyl isoindolinones in MeOH and ⁱPrCN.

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Solvent plays an important role in many chemical reactions. The C−H activation has been one of the most powerful tools in organic synthesis. These reactions are often assisted by solvents which not only provide a medium for the chemical reactions but also facilitate reaching to the product stage. The solvent helps the reaction profile both chemical...