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Fig 3 - A tEMTing target? Clinical and experimental evidence for epithelial-mesenchymal transition in the progression of cutaneous squamous cell carcinoma (a scoping systematic review)

Fig. 3 Signalling for arsenite-induced EMT. Arsenite activates NFκB signalling pathways, which induce EMT via Snail as well as lead to the secretion of IL-6. Autocrine IL-6 signalling induces EMT and activates PI3K signalling via miR-21 mediated repression of PTEN [76]
Signalling for arsenite-induced EMT. Arsenite activates NFκB signalling pathways, which induce EMT via Snail as well as lead to the secretion of IL-6. Autocrine IL-6 signalling induces EMT and activates PI3K signalling via miR-21 mediated repression of PTEN [76]
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