Figure 2 - available via license: Creative Commons Attribution 4.0 International
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Schematics depicting the workflow process for testing (A) viral particle inactivation and (B) viral RNA inactivation.
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Recommendations released by the CDC in 2023 address the need to demonstrate that the RNA genome of positive-strand RNA viruses is inactivated in addition to viral particles. This recommendation is in response to the similarities between host mRNA and the viral genome that allow the viral RNA to be used as a template by host replication mechanisms t...
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