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Schematic representation of ACs NPs through the ski multilayered structure with cancer tumor. The polymeric NPs can penetrate the skin layers and release active compounds in the cancer cells, improving the treatment.
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Amphiphilic copolymers (ACs) are versatile systems with self-assembling and aggregating properties, enabling the formation of nanomaterials (NMs) such as micelles, vesicles, nanocapsules, and nanogels. These materials have been extensively explored for the delivery of various drugs and active compounds, enhancing the solubility and permeation of po...
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Context 1
... capability makes AC NMs particularly suitable for hydrophobic drug delivery in cancer and skin treatments. AC NMs can penetrate the skin through several pathways, including via dermal structures such as hair follicles, intracellularly through corneocytes, and intercellularly around corneocytes (Figure 1) [10]. The route of penetration depends on factors such as the NMs' composition, size, charge, and morphology. ...
