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Background
Despite the frequent co-occurrence of depression and diabetes, gender differences in their relationship remain unclear.
AimsThis exploratory study examined if gender modifies the association between depressive symptoms, prediabetes and diabetes with cognitive-affective and somatic depressive symptom clusters.
Method
Cross-sectional analy...
Contexts in source publication
Context 1
... 17) and 15 052 (51.32%) were female. Moreover, 23 224 (82%) participants were non-diabetic, 2548 (8.52%) were prediabetic and 3847 (9.48%) were diabetic ( Table 2). There was no interaction effect between diabetes status and gender for prediabetes (Table 3, Supplementary Table 3). ...Context 2
... 0.09, CI: 0.00, 0.18, P = 0.039) or known prediabetes (aCoeff. = 0.07, CI: −0.07, 0.22, P = 0.315) had statistically significantly higher mean cognitive-affective symptom cluster scores than non-diabetic individuals in the main analysis; this became significant for diabetes in the sensitivity analysis wherein psychomotor retardation was included in the cognitive-affective symptom cluster (Table 2, Supplementary Table 2). The interaction between diabetes status and gender was statistically significant for diabetes (P = 0.001), but not known prediabetes (Table 3), which was consistent in the sensitivity analysis with psychomotor retardation included in the cognitive-affective cluster (Supplementary Table 3). ...Context 3
... 0.24, CI: 0.13, 0.35, P < 0.001) and diabetes (aCoeff. = 0.30, CI: 0.19, 0.41, P < 0.001) had statistically significantly higher mean somatic symptom cluster scores than non-diabetic individuals (Table 2). Similarly, in the model including an interaction term between gender and known prediabetes or diabetes, the mean somatic symptom scores were statistically significantly higher for the individuals with known prediabetes and diabetes than those with no diabetes; however, these associations did not differ by gender (Table 3). ...