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This study evaluates the antipyretic activity of methanolic leaf extract of Chromolaena odorata in albino rats. Pyrexia, commonly known as fever, is the medical term for an elevated body temperature. It occurs when the body's temperature rises above the normal range, typically over 38°C (100.4°F), as a response to infection, inflammation, or other...
Contexts in source publication
Context 1
... injection of Escherichia coli suspension elevated the rectal temperature after 2 hours of administration. Treatment with paracetamol at a dose of 150 mg/kg and extract of Chromolaena odorata at a dose of 200 and 400 mg/kg decreased the rectal temperature of the rats in a dose-dependent manner (Table 2). It was found that the extract at a dose of 200 and 400 mg/kg caused a significant lowering of rectal temperature at 3 hours following its administration. ...Context 2
... injection of Escherichia coli suspension elevated the rectal temperature after 2 hours of administration. Treatment with paracetamol at a dose of 150 mg/kg and extract of Chromolaena odorata at a dose of 200 and 400 mg/kg decreased the rectal temperature of the rats in a dose-dependent manner (Table 2). It was found that the extract at a dose of 200 and 400 mg/kg caused a significant lowering of rectal temperature at 3 hours following its administration. ...