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Fig 2 - Acute psilocybin enhances cognitive flexibility in rats

Psilocybin improves performance in the set-shifting task. a Average trials-to-criterion across all sets in the baseline period (PRE, open gray circles) and in the acute psilocybin condition (PSI, blue circles, n = 15). ***p = 0.0005, paired t-test. b Number of completed sets in baseline and psilocybin conditions, p = 0.546, Wilcoxon sign-rank test. c Response time in baseline and psilocybin conditions. **p = 0.008, Wilcoxon sign-rank test. d Fraction of correct responses across all sets in baseline and psilocybin conditions. e Number of streaks of consecutive correct responses averaged across all sets, in baseline and psilocybin conditions. *p = 0.025, Wilcoxon sign-rank test. f Average length of streaks averaged across all sets, in baseline and psilocybin conditions. *p = 0.034, paired ttest. g Average trials-to-criterion for baseline (PRE, gray open circles) and saline conditions (SAL, brown circles, n = 14). h Number of completed sets in baseline and saline conditions. i Fraction of correct responses across all sets in baseline and saline conditions.
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