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Ethno-medicinal uses of Flemingia strobiifera in the Magar communities at Kawaswoti urban municipality, Province no. 4, Nepal was surveyed. Phytochemicals present in the hexane and aqueous methanolic extracts of the roots were evaluated by chemical tests and GC-MS analysis. The antimicrobial activity of the extracts was carried out against 8 bacter...
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Context 1
... the aq. methanolic extract, 5 compounds were identified (Table 2). Phthalic andydride (36.62%), n-hexadecanoic acid (20.67%), 3,5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one (11.36%), 1-heptadecene (8.76%) and octadecanoic acid (5.28%) were the main constituents accounting 82.69% of the total constituents. ...Context 2
... the aq. methanolic extract, 5 compounds were identified (Table 2). Phthalic andydride (36.62%), n-hexadecanoic acid (20.67%), 3,5-dihydroxy-6-methyl-2,3-dihydro-4H-pyran-4-one (11.36%), 1-heptadecene (8.76%) and octadecanoic acid (5.28%) were the main constituents accounting 82.69% of the total constituents. ...Similar publications
Nigella sativa popularly known as black seed has gained popularity for a wide range of medicinal applications due to its seeds which are rich in phytochemicals. Different extracts of Nigella sativa seeds were obtained by maceration and extraction using four solvents (water, methanol, ethylacetate and hexane). The obtained extracts were tested for t...
Citations
... [6][7][8][9] Many distinctive research studies have been carried out by validating the usefulness of this species in conventional medicine during the past few years. [10][11][12] For example, characterisation of anatomical features [5,13,14] ethnomedicinal importance [15][16][17] economic benefits, [18] phytoconstituents [19,20] and various pharmacological activities such as anthelminthic, [21] analgesic, [9,10] anti-inflammatory [10,22] antioxidant activity, [23,24] anti-anxiety activity, [25] anticonvulsant, [26] anti-ulcerogenic activity, [27] antimicrobial activity, [14,19] antidiabetic activity, [28] wound healing activity [29] and estrogenic activity. [11] So far, there is no complete library search has been carried out on F. strobilifera using available data collected from different published articles. ...
... Nemkul et al. [12] ...
... [6][7][8][9] Many distinctive research studies have been carried out by validating the usefulness of this species in conventional medicine during the past few years. [10][11][12] For example, characterisation of anatomical features [5,13,14] ethnomedicinal importance [15][16][17] economic benefits, [18] phytoconstituents [19,20] and various pharmacological activities such as anthelminthic, [21] analgesic, [9,10] anti-inflammatory [10,22] antioxidant activity, [23,24] anti-anxiety activity, [25] anticonvulsant, [26] anti-ulcerogenic activity, [27] antimicrobial activity, [14,19] antidiabetic activity, [28] wound healing activity [29] and estrogenic activity. [11] So far, there is no complete library search has been carried out on F. strobilifera using available data collected from different published articles. ...
... Nemkul et al. [12] ...
... Work has been done on various species of Flemingia like F. [57][58][59] , F. macrophyla 60 , F. chappar 61 , F. philippinensis 62 , F. faginea 48 , F. grahmiana 63 F. stricta 64 , etc. but no phytochemical work has been found in the literature on the species F. praecox. However, these species have shown the presence of phenols, flavonoids, steroids, tannins, www.nature.com/scientificreports/ ...
Globally, 15–24% couples are unable to conceive naturally and 50% of cases of this problem are due to infertility in males. Of this, about 50% of male infertility problems are developed due to unknown reasons called as idiopathic infertility. It is well established that, reactive oxygen species (ROS) have negative impact on male fertility and are involved in 80% of total idiopathic male infertility cases. Medicinal plants are considered as an alternative approach for mitigating the health problems. The plants with good antioxidant capacity can improve the male infertility symptoms generated by ROS. Such medicinal plants can be used to alleviate the symptoms of male infertility with their diverse phytoconstituents. Mucuna pruriens is a well-accepted herb, with its seeds being used to improve the male fertility in various ways and one of the ways is by eliminating the ROS. In our field survey, another plant, Flemingia praecox, although less known, its roots are used in all problems related to the male fertility by tribal people of the Gadchiroli district of Maharashtra, India. The study was conducted to determine in vitro antioxidant potential of F. praecox and compared the results with the well-established male fertility improving plant M. pruriens with special emphasis on medicinally important roots of F. praecox and seeds of M. pruriens. The objective of the study was investigated by studying their total phenol (TPC) and flavonoid (TFC) content, antioxidant parameters (DPPH, FRAP, ABTS, DMPD, β-carotene bleaching and TAA) and finally DNA damage protection capacity of the plant extracts was studied. The plant parts used for the medicinal purposes have been investigated along with other major parts (leaves, stem and roots of both the plants) and compared with synthetic antioxidants, BHA, BHT and ascorbic acid. Moreover, the inhibition of two male infertility enzyme markers, PDE5 and arginase by F. praecox root and M. pruriens seed extract was also studied in vitro. The results showed that F. praecox possesses higher antioxidant activity than M. pruriens in the majority of studies as observed in TFC, DPPH, TAA, ABTS and DMPD assays. However, M. pruriens seeds showed best results in TPC, FRAP and DNA damage protection assay. F. praecox root extract also gave better PDE5 inhibition value than M. pruriens seeds. This study will help to establish the authenticity of F. praecox used by tribal people and will encourage its further use in managing the male infertility problems.
... Taqueer and Itankar evaluated anti-inflammatory activity of aerial of plant using methanolic and hydro alcoholic extracts[19].• Roots: Nemkul, Bajracharya and Shrestha reported in vitro antimicrobial activity of roots using Hexane and 70% Methanol extract using GC-MS technique[26]. Soe, Thein and Oo evaluated wound healing property using 70% ethanolic root extract[27]. ...
