Panel A: isosurfaces of the shortest distance calculated in three muscles, vastus lateralis (blue shade), vastus intermedius (green), and rectus femoris (dark red) starting from the surface of modeled GTV with í µí¼† 3 = 10, í µí¼† 3 = 20, and í µí¼† 3 = 40. The outermost contour corresponds to the largest value of í µí¼† 3 . Panel B: three levels of isosurfaces of shortest distance with í µí¼† 3 = 10. The boundary of the fat, femur, and noninvolved muscles completes the modeled CTV.

Panel A: isosurfaces of the shortest distance calculated in three muscles, vastus lateralis (blue shade), vastus intermedius (green), and rectus femoris (dark red) starting from the surface of modeled GTV with í µí¼† 3 = 10, í µí¼† 3 = 20, and í µí¼† 3 = 40. The outermost contour corresponds to the largest value of í µí¼† 3 . Panel B: three levels of isosurfaces of shortest distance with í µí¼† 3 = 10. The boundary of the fat, femur, and noninvolved muscles completes the modeled CTV.

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Objective: Soft-tissue sarcoma spreads preferentially along muscle fibers. We explore the utility of deriving muscle fiber orientations from diffusion tensor MRI (DT-MRI) for defining the boundary of the clinical target volume in muscle tissue. Approach: We recruited eight healthy volunteers to acquire MR images of the left and right thigh. The ima...

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Context 1
... model the CTV in muscle tissue, we started by placing a model spherical GTV of 22.5 mm radius within vastus lateralis and vastus intermedius muscles. In Fig. 5 Panel A, the isosurfaces of shortest distance are shown for three values of the largest eigenvalue í µí¼† 3 . It is expected that in the ideal case of a single dominant direction the asymmetry scales as √í µí¼† (see phantom case experiments in Fig. A.1 in the ...
Context 2
... a given asymmetry, the distance from the GTV models a particular CTV boundary. Fig. 5 Panel B shows the candidate CTV boundaries obtained by solving ...

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Objective: Soft-tissue sarcoma spreads preferentially along muscle fibers. We explore the utility of deriving muscle fiber orientations from diffusion tensor MRI (DT-MRI) for defining the boundary of the clinical target volume (CTV) in muscle tissue. Approach: We recruited eight healthy volunteers to acquire MR images of the left and right thigh...