Pain location in the subgroups under investigation.

Pain location in the subgroups under investigation.

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Background The aim of this work is to analyze reports of migraine attacks collected online in the citizen science project CLUE with respect to gender- and migraine type-specific differences in drug effectiveness and pain perception. Citizen science project data collection opens the possibility to examine these differences based on a large number of...

Contexts in source publication

Context 1
... participants had three different possibilities-only leftsided, only right-sided and bilateral pain-to specify the pain location. Figure 5 shows the distribution of the specified pain locations in the selected groups. ...
Context 2
... p < 0.05, ** p < 0.01, *** p < 0.001. The p values indicate the results for the comparison (chi-square tests) of the distribution in the groups considered (see also Figure 5). * p < 0.05, ** p < 0.01, *** p < 0.001. ...


... The results of all previous studies were obtained using self-reported questionnaires, and the studies did not directly determine attack frequencies during school and vacation periods. The CLUE research project directly determined migraine attacks, thereby creating a database for future studies [8,9]. ...
    This citizen science project CLUE compared the attack frequency between school and vacation periods among adolescents. The data collection process adopted in citizen science projects opens up the possibility of conducting analyses by including a large number of participants over a long period and across different regions. The data on 684 migraine attacks reported by 68 adolescents aged 16 to 19 years were collected using an online platform and smartphone apps. A Fisher’s exact test was used to compare the distributions of the migraine attack frequency during vacation and school periods in two different scenarios. In both scenarios, the attack frequency during school periods was significantly higher than that during vacation periods. The use of web-based data collection has some methodological limitations; however, it enabled the measurement of relative migraine attack frequency in students during vacation and school periods. The higher prevalence of migraine during school periods indicates the requirement of increasing headache awareness among children.