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Nevus araneus (spider nevus). In the center of the red lesion a small (1 mm) red papule is visible, surrounded by several distinct radiating vessels. Pressure on the lesion causes it to disappear. Blanching is replaced by rapid refill from the central arteriole when pressure is released.
Source publication
Skin diseases on the nose are seen in a variety of medical disciplines. Dermatologists, otorhinolaryngologists, general practitioners and general plastic and dermatologic surgeons are regularly consulted regarding cutaneous lesions on the nose. This article is the second part of a review series dealing with cutaneous lesions on the head and face, w...
Context in source publication
Context 1
... nevi show a spider-like growth pattern with a pin head-sized central arterial vascular nodule and small vas- cular radiations in a starburst-like pattern (Fig. 7). When they appear in abundance, spider nevi can be a clinical sign of heavy liver illness or carcinoid syndrome. The most frequent localization is the face and upper body. Under light compression with a glass spatula, arterial pul- sations can be recognized in the center, fading toward the periphery. Therapy consists of laser therapy ...Citations
... MM has a dual etiologic pathway: 70% of MM tumors occur de novo, and 30% originate from pre-existing common nevi [3][4][5]. ...
... CSSC commonly presents as a crusting erythematous ulcer with a red granular base and a tendency to bleed with minor trauma ( Figure 2). Chronic ulcers found on top of scar tissue that do not heal should raise concern for CSCC [4]. Only 5.2% of facial CSSC is found on the nose, with the majority of facial CSSC (39.5%) on the buccal or parotid-masseteric units [36]. ...
... Treatment: Mohs micrographic surgery is the preferred modality of choice in treating HNCSCC [41]. Although a margin of 4 mm for lesions smaller than 2 cm and a margin of 6 mm for lesions greater than 2 cm has been suggested, no large studies have been conducted to confirm these values [4,42]. CSCC is highly sensitive to RT; however, risk of bone necrosis, cataracts, and uncertain cosmetic outcomes limit it as an adjuvant therapy for the face [43,44]. ...
The nose is a structure of both cosmetic and functional importance. Cutaneous lesions of the nose occasionally represent a diagnostic challenge and involve the expertise of several specialties from dermatology, otolaryngology—head and neck surgery, infectious disease, and pathology, among others. We present a review of salient features of malignant and benign cutaneous nasal lesions which are of importance to physicians treating these complicated pathologies.
... Additionally, it is employed in the treatment of burns, acne, neurodermatitis, herpes simplex and genitals, and fungal infections of the eyes and vagina [33]. We isolated active chemicals for antioxidant, anti-inflammatory, and anti-acne from T. biroi propolis extracts because no prior research has reported the evaluation of this plant's propolis in anti-acne products [1]. ...
... Several compounds are isolated from T. biroi propolis, some of which have biological activity and others do not. These include sulabiroins A, (2S)-5,7dihydroxy-4′-methoxy-8-prenylflavanone acid, broussoflavonol F [43] which inhibits the activity of the SARS-CoV-2 protease, sulabiroins B, such as sulabiroins A, (2S)-5,7-dihydroxy-4′-methoxy-8-prenylflavanone acid and broussoflavonol F [43] as an inhibitor of SARS-CoV-2 protease activity; sulabiroins A, sulabiroins B, 2′,3′-dihydro-3′-hydroxypapuanic acid, ( )-papuanic acid, ( )-isocalolongic acid, isopapuanic acid, isocalopolyanic acid, glyasperin A, broussoflavonol F, (2S)-5,7-dihydroxy-4′-methoxy-8-prenylflavanone, isorhamnetin, (1′S)-2-trans, 4-transabscisic acid, and (1′S)-2-cis,4-trans-abscisic acid [44] as inhibitors of XO activity; calophylloidic acid A for antibacterial activity against Staphylococcus aureus and Escherichia coli [45]; 4-(4′-hydroxy-3′-methoxyphenyl)-3,5,7-trihydroxycoumarin, sulawesins A and sulawesins B [46] as inhibitors of XO activity; glyasperin A, propolin E and propolin A [47] for cytotoxicity in breast (MCF-7) and colon (HT-29 and HCT-116) cancer cells; pinobanksin-5,7-dimethyl ether, artepillin C, luteolin-5-methyl ether, pinobanskin-3-0 (butyrate or isobutyrate) and kaempferide [48]; propolin A, propolin E, propolin H, and glyasperin A [1,49]. ...
Many branches of medicine treat skin conditions that manifest on the nose. When people experience skin lesions on the nose, they often seek the advice of dermatologists, otorhinolaryngologists, primary care physicians, and general plastic and dermatologic surgeons. Skin lesions on the face and head are common in dermatologic surgeons’ daily practice, and this article is part two of a review series covering this topic. When assessing skin diseases on the nose or planning the reconstruction of surgical defects, it is essential to consider the nose skin’s special anatomical and histological features. Areas of the skin that are thinner, less sebaceous, and more pliable include the dorsum, columella, and sidewalls. There is thicker, more sebaceous, adhesive, and less flexible skin around the nasal tip and alae. The cosmetic industry has invested significantly in propolis for acne treatment, particularly in cosmeceuticals. Dermo-cosmetics containing up to 4% propolis can effectively prevent and treat acne vulgaris thanks to its anti-inflammatory, antibacterial, healing, and immunomodulatory properties.
... Both conditions are influenced by significant risk factors such as fair skin phototype, commonly found in the Caucasian population, and exposure to ultraviolet (UV) radiation [1][2][3]. Additionally, both BCC and rosacea tend to manifest primarily in the central area of the face, particularly the nose [1][2][3][4]. However, rosacea primarily affects young women, typically presenting after the age of 30, while BCC is more commonly seen in elderly males, typically in their seventh or eighth decade of life [3,5]. ...
Introduction
The relationship between rosacea and basal cell carcinoma (BCC) is still not known. Almost all reports questioning the relation between BCC and rosacea are focused on rhinophyma.
Aim
To examine the possible connection of BCC and rosacea.
Material and methods
110 patients with BCC located on the face treated surgically in the Dermatosurgery Unit in 2020-2021 were included in the study. A trained dermatologist assessed the presence or absence of concomitant rosacea and assessed its severity according to the Investigator’s Global Assessment (IGA).
Results
Fifty-one (46.4%) subjects with BCC and concomitant clinically diagnosed rosacea were found. In our group 35.5% of women had BCC located on the cheeks, while in men most cancers were located on the nose (55%, n = 11), however this difference has not reached statistical significance.
Conclusions
The incidence of rosacea in our population was undoubtedly higher, comparing to the normative population. Both rosacea and BCC share the same risk factors – UV exposure, the potential association should not be neglected.
... In facial hemangiomas, 15.8% show involvement of the nose, and the nasal tip is affected in 5.1%. 4,5 We are reporting a rare case of haemangioma at the soft triangle aesthetic subunit of the external nose. ...
Hemangiomas of the nose are very rare lesions.They may be found in both paediatric and adult population.The various modalities of treatment may range from medical management to surgical management.We are reporting a benign vascular lesion near the nasal tip at the soft triangle aesthetic subunit in a 64 year old male which was treated by simple surgical excision using electrocautery and primary closure. Histopathological examination of excised specimen confirmed the diagnosis as hemangioma.
... Since the patient's nose was involved with cutaneous sarcoidosis, there were many considerations regarding the location of the nose and its importance from an aesthetic point of view [7]. The nose is the central part of the middle face and has an essential aesthetic, functional, and psychological role [7]. ...
... Since the patient's nose was involved with cutaneous sarcoidosis, there were many considerations regarding the location of the nose and its importance from an aesthetic point of view [7]. The nose is the central part of the middle face and has an essential aesthetic, functional, and psychological role [7]. ...
... The lesion on our patient's nose mimics rhinophyma due to the clinical features of rhinophyma that were common in our patient. Rhinophyma is characterized by erythema and telangiectasias with progressive enlargement of the nose [7,8]. The diagnosis of Lupus erythematosus was also considered due to its varied expression of the clinical presentation, which can include erythema and telangiectasias [9]. ...
Sarcoidosis is a granulomatous disease that involves multiple systems. Cutaneous involvement can manifest in patients with sarcoidosis and can present with or without systemic involvement. We present a case of cutaneous sarcoidosis in a Syrian woman that showed improvement after a combination of methotrexate and prednisolone therapy. The patient had unusual chest radiography findings and developed an unexplained fissured tongue after 5 days of receiving methotrexate therapy. In addition, the patient developed indurated erythematous plaque and papules on her upper right arm at the same location as a performed biopsy, which increased the diagnosis of a newly formed scar sarcoidosis although she was receiving her treatment.
... Therefore, cutaneous lesions of nose are very easily noticed by the patients themselves and other people. The high concentration of sebaceous glands, increased ultraviolet radiation exposure, and genetic abnormalities account for the various benign and malignant cutaneous lesions of the nose such as rhinophyma, hemangioma, squamous cell carcinoma, melanoma, basal cell carcinoma, etc. 1 Papillary carcinoma, also known as digital papillary adenocarcinoma, is a rare tumor of the sweat glands, which is mainly localized to the digits. The presence of such a lesion in the face is very rare. ...
The skin of the nose is a common site for various benign and malignant lesions. Herein, we report a cutaneous nodular lesion on the dorsum of the nose in an 80-year-old female, which was surgically excised under local anesthesia. On histopathological examination, she was diagnosed with papillary carcinoma, a very rare disorder at such a location. The patient was followed-up and no recurrence was noted.
... Initially, clown nose-like lesion was considered as a indicator of cutaneous metastatic malignancies, including lung cancer (2), renal clear cell carcinoma (3), rhabdomyosarcoma (4), cervical cancer (5), and liver cancer (6). In clinical practice, however, it can also be a cue for genetic syndromes, such as Tricho-Rhino-Phalangeal syndrome (7), as well as some primary nasal diseases including infections such as leishmaniasis (8), inflammations such as rosacea (9), and tumors such as keratoacanthoma (10). ...
Clown nose-like lesion refers to the manifestation of a reddish or skin-colored bulge on the tip of the nose or the manifestation of bulbous tip of the nose. More and more clinical cases show that clown nose-like lesion can also be the indication of some genetic syndromes, not just the manifestation of metastatic visceral tumor as it initially proposed. However, the clinical features of clown nose-like lesion indicated by metastatic malignancies, genetic cancer predisposition syndromes or primary diseases involving the nasal tip are lacking. In this study, patients with clown nose-like lesion in our clinical practices and from published literatures were collected and reviewed. We found that clown nose-like lesions caused by metastatic malignancies including lung cancer are often solitary and more common in male (24/31) older individuals (average age 62.3, ranging 40–78 years old). In addition, they usually appear for a short time, and are prone to be misdiagnosed as primary nasal diseases, leading to a poor prognosis (all patients with data available died within 4 months). Clown nose-like lesions associated with genetic cancer predisposition syndromes usually develop at a young age (mean age 15.3) with female preference (9/10). They are accompanied by multiple-systemic involvements, including low hair volume, developmental delay, cancer predisposition or neurological diseases. They show slow development and often positive family history (6/10). These two kinds of clown nose-like lesions are often asymptomatic, which delays the diagnosis and treatment of underlying malignancies or syndromes. In brief, the term of clown nose-like lesion is underrecognized, and should be updated. Clown nose-like lesions can serve as indicators to at least three categories of clinical issues: metastatic visceral tumors, genetic syndromes, and primary diseases involving the nasal tip. Increased awareness of clinical features of updated clown nose-like lesions can alert physicians to these underlying malignancies or syndromes, render earlier detection of associated medical issues, and allow for genetic counseling of family members.
... Eponymous terms: Cauchois-Eppinger-Frugoni syndrome; Eppinger's spider naevus Alternative terms: portal vein thrombosis; star (spider) angioma (see Sand et al. 2010, Thomas 2016 Hans Eppinger was an Austrian internist, professor, and director of an internal medicine clinic in Vienna. He conducted seawater potability experiments on Gypsy prisoners in the Dachau concentration camp. ...
This work focuses on a specific type of terminological variants, i.e. medical eponymous terms gradually replaced by alternative, noneponymous terms. This descriptive study is conducted on a controlled medical terminology set – the International Classification of Diseases (ICD) of the World Health Organization (WHO). The focus of the study is on the eponymous terms named after physicians associated with the Nazi regime. The aim is to analyse if these eponyms were included in ICD-10 and if they were transferred into the new, 11th version of the Classification. Of all the eponymous terms presented in the paper, seven were found in ICD-10. The overall result of this study indicates that the eponymous terms associated with the Nazi regime have been replaced with alternatives or removed from the 11th version of the International Classification of Diseases in all cases, except for Creutzfeldt-Jakob disease.
... Rhinophyma is a slow-growing and disfiguring enlargement of the nose that primarily occurs in men aged 50-70 years. Established rhinophyma is characterized by a large bulbous nose, wide pores, thick skin, and telangiectasia [2]. It is considered to be a characteristic of an advanced stage of phymatous rosacea. ...
Rhinophyma is a benign condition characterized by a large, bulbous nose with prominent pores. It is commonly associated with untreated cases of rosacea. The disease can carry a substantial psychological impact that causes patients to seek advice about how to improve their physical appearance. Many treatment options are available for rhinophyma, but there is no standard treatment protocol. Here, we describe the case of a 65-year-old man with a large rhinophyma that caused him cosmetic and psychosocial embarrassment. The condition was treated by surgical excision and bipolar electrocautery. No complications occurred after the procedures, and healing was completed 2 weeks later by secondary intention and reepithelialization. A simple surgical removal using a scalpel to shave off the abnormal tissue with electrocauterization of the bleeding points can be considered as a good treatment option for rhinophyma, as it results in an excellent cosmetic outcome and has short recovery time.
... Previous literature has demonstrated other skin conditions mimicking this diagnosis including angiosarcoma, squamous cell carcinoma and sarcoidosis. 2 A 52-year-old woman was referred to ear, nose and throat (ENT) from dermatology for surgical management of rhinophyma. She described a 3-year history of an increasing swelling on the tip of her nose (figure 1). ...
