Multinomial regression analysis for associations between life adversities and probability of profile assignment in men

Multinomial regression analysis for associations between life adversities and probability of profile assignment in men

Source publication
Article
Full-text available
People commonly face adverse circumstances throughout life, which increases risk for psychiatric disorders, such as anxiety, depression, psychosis, and posttraumatic stress disorder (PTSD). Adversities may occur during different periods in life. Especially adversity during early periods has been suggested to put individuals at risk for adverse ment...

Contexts in source publication

Context 1
... were fixed in case of empty cells in the joint distribution of predictors, covariates, and latent profile variables. 61 Results are given as log odds indicating the probability likelihood for classification into the target profile versus the reference lowsymptom severity profile (Tables 3 and 4). A False Discovery Rate threshold (5%) was applied to correct the alpha value for significance for multiple comparisons. ...
Context 2
... found a significant association between undernutrition in early gestation and profile assignment in men (Table 3). Findings suggested that in men exposed to famine during early gestation, probability was higher for classification into the mild-than lowsymptom profile compared to unexposed men. ...
Context 3
... found significant associations between childhood traumatic maltreatment and profile assignment in men (Table 3) and women (Table 4). Findings suggested that men who reported to have experienced more childhood maltreatment were associated with higher probability for classification into the anxious/depressive and high-than the low-symptom profile. ...
Context 4
... adulthood trauma We found significant associations between adulthood trauma and profile assignment in men (Table 3) and women (Table 4). In men, reports of experiencing more adulthood trauma was associated with higher probability for classification into the high-than lowsymptom profile. ...

Citations

... In one exception, a very small sample using the naturalistic experiment of a severe ice storm found associations between maternal pregnancy exposure and broad autism phenotype in offspring during young adulthood (Li et al., 2023). In a larger sample, extensions of the Dutch Famine Study into late adulthood (mean age 73 years) continue to find effects of adversity in pregnancy and psychological health at these older ages (Hilberdink et al., 2023). Although multidecade follow-up is still rare, the findings published to date suggest persistence of risk for many individuals. ...
... To truly understand, examinations across all developmental timepoints, across exposure and outcome types, will be important. It is intriguing to note that in one of the few prenatal programing studies of older adults (Hilberdink et al., 2023) the consequences of pregnancy adversity on psychological health persisted into late adulthood only for men. Certainly, more work in this space will be informative. ...
Article
Full-text available
In this article, I highlight core ideas, empirical findings, and advances in the study of how stress during pregnancy may prenatally program child neurodevelopmental, psychopathological, and health outcomes, emphasizing reviews, metanalyses, and recent contributions of conceptual and empirical work. The article offers a perspective on the history of this area of science, the underrecognized contributions of influential scholars from diverse fields of study, what we know from the evidence to date, the persistent challenges in sorting through what is left to learn, and suggestions for future research. I include sections focused on promoting resilience, pregnancy interventions that demonstrate positive effects across two generations, and the translational implications of the accruing data for practice and policy, highlighting opportunities for integrating across a range of fields and sectors. In the concluding sections, I discuss lessons learned from conducting this work and provide a closing summary of progress and future directions. The goal of this writing was to provide a viewpoint on some ways that emerging intergenerational transmission scholars might responsibly contribute to the future of the field of developmental psychopathology.