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... pallida, colloquial named yellow tulp ( Fig. 1), is one of the cardiac glycoside-containing plants that collectively are the most important cause of plant associated poisoning of livestock in southern Africa ( Kellerman et al. 1996). M. pallida is strongly aversive when ingested by livestock. It is generally accepted among farmers in South Africa that stock raised on M. pallida ...

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... Similar to Moraea pallida (Snyman and Kellerman 2023), S. latifolius is an aversive poisonous plant. It is commonly accepted among South African farmers that livestock familiar with S. latifolius will not be poisoned when grazing on infested pastures. ...
... The objective of this research was to isolate the substance present in S. latifolius that causes aversion when eaten by livestock. The aversive substance present in M. pallida was previously isolated by using the sensory receptors of a sheep to detect the presence of the aversive substance in chemical fractions made from the plant (Snyman and Kellerman 2023). It was the aim of this investigation to replicate this approach in isolating the aversive substance of S. latifolius. ...
... The results furthermore show that the aversive substance isolated was also the toxic principle of the plant. These findings confirm corresponding results previously obtained with Moraea pallida (Snyman and Kellerman, 2023). Contrary to the fact that sheep averted to S. latifolius could sense the toxic principle in the various chemical fractions, in the more purified fractions even at a distance from the trough, sheep averted to the toxic principle or chemical fractions containing the toxic principle did not refuse S. latifolius. ...
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The aversive substance of Senecio latifolius was isolated by means of the sensory receptors of sheep averted to S. latifolius. Chemical fractions refused due to the presence of the aversive substance sensed by the sheep were fractionated until a purified substance had been isolated. Nuclear magnetic resonance (NMR) analysis of the purified substance showed it to be sceleratine nitrogen oxide, the toxic principle of S. latifolius.