MicroRNA-mRNA interaction.  

MicroRNA-mRNA interaction.  

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MicroRNAs are small non-coding RNAs that can negatively regulate gene expression on a post-transcriptional level and have been shown to interact with epigenetic mechanisms like DNA methylation. Methyl CpG binding protein 2 (MeCP2) is a protein that recognizes methylated DNA sequences and can thus modulate gene expression. MeCP2 expression is downre...

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Context 1
... Forman and Coller, 2010;Jones-Rhoades and Bartel, 2004). In animals, microRNAs regulate gene expression by imperfectly base pairing in the 3úntranslated region of their target mRNA inhibiting protein synthesis or causing mRNA degradation (Figure 7). ...