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Mapping of relevant research addressing health-based questions: number of relevant studies of each methodology, plus references to the most relevant studies.
Source publication
Vitamin A deficiency is a major health risk for infants and children in low- and middle- income countries. This scoping review identified, quantified, and mapped research for use in updating nutrient requirements and upper limits for vitamin A in children aged 0 to 48 months, using health- based or modelling-based approaches. Structured searches we...
Contexts in source publication
Context 1
... considered the types of studies that would help to answer both the health-based and modelling-based questions in setting the inclusion criteria. The inclusion criteria are set out in full in Supplementary Table S1. What is the relationship between exclusive or mixed breastfeeding duration and vitamin A status? b. ...Similar publications
Nutrient deficiency is a major cause of different health disorders in human beings. Malnutrition has become more alarming in under-developed countries and might affect more than 3 billion people in the world. Supplementation and food fortification of vegetable crops with minerals can address the issue of adequate nutrition security. Current study w...
Citations
... Deficiency of vitamin A represents a serious pediatric health hazard in countries of low-and middle income [29]. Deficient Vitamin A can be injurious to development of the brain in fetus and in newborns can cause high susceptibility to bronchopulmonary dysplasia and increase the possibility of inflammation [30,31]. ...
Background
Neonates with intrauterine growth retardation (IUGR) may present with fatal complications and permanent serious consequences. Vitamin status may influence fetal development. In this study we assessed vitamin A, E and D concentrations in umbilical cord blood in newborns with IUGR.
Methods
Maternal data were obtained. Neonatal assessment included; age of gestation calculated from last menstrual period, Ultrasound (U/S), new Ballard, Apgar scores and anthropometric measurements including; Head circumference, length and weight. WHO growth percentile curves were used. Vitamin A, E and D in cord blood samples were measured by high performance liquid chromatography (HPLC) and ELISA consecutively.
Results
A total of 86 full term newborns were enrolled in this study, 42 (48.8%) with IUGR with gestational age (33.59 ± 1.20) week by U/S and 44 (51.2%) appropriate for gestational age neonates with gestational age (38.70 ± 1.50). Ballard and Apgar scores (p < 0.05) and Z scores for weight, length and head circumference (p < 0.001) at birth were significantly lower in neonates with Intrauterine growth retardation (IUGR) than appropriate for gestational age (AGA) neonates. The levels of Vitamin A, E and D were significantly lower in the IUGR group than the AGA (p < 0.05) for all. Significant positive correlations of weight with vitamin A, and E cord blood levels were found (p < 0.05), while length was significantly positively correlated only with vitamin A (p < 0.05). Head circumference showed significant positive correlations with the three vitamins (p < 0.05) for all.
Conclusion
Neonates with IUGR had significantly lower levels of Vitamin A, E and D than AGA neonates. Significant positive correlations of weight with vitamin A, and E cord blood levels was detected, while neonatal length was associated only with vitamin A level. The present study highlights the significance of nutritional policies for inhibiting deficiency of these vitamins during pregnancy and childhood.
Yogurt is one of the most nutritious probiotic food and serves as a medium for nutrients supplementation. The prevalent deficiency of iron and vitamin A within the population prompted the creation of retinol acetate and iron-fortified yogurt. In the yogurt-making process, temperatures typically remain below 100°C for 5 to 10 minutes, and the fortified milk exhibited remarkable heat stability, surpassing even the effects of sterilization treatment (140°C for over 20 minutes). Sensory evaluations of the fortified yogurts yielded scores comparable to the control yogurt. The fortified variety set in a similar time frame, and the quantity of microorganisms used in the inoculation mirrored that of the control yogurt. Acetaldehyde, a key flavoring compound, was produced in a similar manner to the control yogurt (p>0.05). Physico-chemical properties of the fortified yogurt closely resembled those of the control, with improvements seen in viscosity and textural attributes, though these values were statistically similar (p>0.05). The fortified yogurt demonstrated stability along with consistent quality, texture, and sensory appeal, suggesting its potential for commercialization to address nutrient deficiencies.
Background and Objectives: childhood anemia is highly prevalent worldwide and its effective treatment is the cornerstone to improve health of these children. This study was conducted to compare the mean rise in haemoglobin (Hb) after iron-alone versus the combination of vitamin-A & iron supplementation in childhood iron-deficiency anemia.Methods: This randomized controlled trial was done at Paediatrics Medicine Department, Jinnah Hospital, Lahore from January-2019 to June-2019. A total of 60 cases, as per inclusion criteria were enrolled from the Paediatric Medicine Department of Jinnah Hospital Lahore. Group-A was supplemented with a combination of vitamin-A and iron while Group-B patients were supplemented with Iron alone. Hb was checked at baseline and after 3 months of treatment as per the designated group. All information, as per predesigned proforma, was entered and interpreted using SPSS version 23.0. An Independent sample t-test was applied and a p-value < 0.05 was considered statistically significant.Results: Sixty patients were included, keeping 30 in each group i.e. Group-A (Vitamin-A + Iron) & Group-B (Iron-alone). In both groups, most of the patients were male, i.e. 22(73.3%) and 23(76.7%) in group-A and group-B respectively. In group-A, the mean age was 1.96±1.6 years while 2.12±1.5 years in group-B. In group-A, the mean rise in Hb level after 3-months of treatment was 3.0±0.99 g/dl, on the other hand, it was 1.96±1.00 g/dl in group B, with a p-value of 0.00014.Conclusion: Vitamin-A supplementation combined with iron replacement therapy is recommended for substantial improvement among children with iron deficiency anemia.Keywords: Vitamin-A, Iron-Supplementation, Hemoglobin (Hb), Iron Deficiency Anemia (IDA).
Nutrition influences health throughout the life course. Good nutrition increases the probability of good pregnancy outcomes, proper childhood development, and healthy aging, and it lowers the probability of developing common diet-related chronic diseases, including obesity, cardiovascular disease, cancer, and type 2 diabetes. Despite the importance of diet and health, studying these exposures is among the most challenging in population sciences research. US and global food supplies are complex; eating patterns have shifted such that half of meals are eaten away from home, and there are thousands of food ingredients with myriad combinations. These complexities make dietary assessment and links to health challenging for both population sciences research and for public health policy and practice. Furthermore, most studies evaluating nutrition and health usually rely on self-report instruments prone to random and systematic measurement error. Scientific advances involve developing nutritional biomarkers and then applying these biomarkers as stand-alone nutritional exposures or for calibrating self-reports using specialized statistics.
Expected final online publication date for the Annual Review of Public Health, Volume 44 is April 2023. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.
