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Landmark studies comparing intensive insulin therapy and conventional management
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Glucose control in patient admitted to the intensive care unit has been a topic of much debate over the past 20 years. The harmful effects of uncontrolled hyperglycemia and hypoglycemia in critically ill patients is well established. Although a large clinical trial in 2001 demonstrated significant mortality and morbidity benefits with tight glucose...
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Context 1
... targets for critically ill patients have shifted over time based on a litany of studies comparing intensive insulin therapy (IIT) to conventional glucose management over the last two decades (Table 1) [11][12][13][14][15][16][17]. Strategies and targets for glycemic control in critically ill patients were variable before the early 2000s. ...Similar publications
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Introduction:
While there have been continued advances in insulin treatment for diabetes since the discovery of insulin 100 years ago, some unmet needs still remain, including those related to mealtime insulin (MTI). The objective of this study was to explore the impacts related to MTI and the relative burden of the impacts on people with diabetes...
