LEfSe was used to compare the microbial variation of the KRAS (a), TP53 (b), APC (c), and PIK3CA (d) groups. The criteria for feature selection were an LDA score > 4 and a p < 0.05

LEfSe was used to compare the microbial variation of the KRAS (a), TP53 (b), APC (c), and PIK3CA (d) groups. The criteria for feature selection were an LDA score > 4 and a p < 0.05

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Studies of both, microbiota and target therapy associated with gene mutations in colorectal cancer, (CRC) have attracted increasing attention. However, only a few of them analyzed the combined effects on CRC. we analyzed differences in intestinal microbiota of 44 colorectal cancer patients and 20 healthy controls (HC) using 16S rRNA gene sequencing...