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Kaplan-Meier for patients with a baseline lactate ≥ 2 mmol/L (red line) compared to patients with a baseline lactate < 2 mmol/L (blue line) (3-month mortality, ± standard deviation)

Kaplan-Meier for patients with a baseline lactate ≥ 2 mmol/L (red line) compared to patients with a baseline lactate < 2 mmol/L (blue line) (3-month mortality, ± standard deviation)

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Purpose: Lactate is an established prognosticator in critical care. However, there still is insufficient evidence about its role in predicting outcome in COVID-19. This is of particular concern in older patients who have been mostly affected during the initial surge in 2020. Methods: This prospective international observation study (The COVIP study...

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Context 1
... the multivariable analysis, the maximum lactate concentration on day 1 was independently associated with ICU mortality (aOR 1.06 95% CI 1.02-1.11; p = 0.007), 30-day mortality (aOR 1.07 95% CI 1.02-1.13; p = 0.005) and 3-month mortality (aOR 1.15 95% CI 1.08-1.24; p < 0.001) after adjustment for age, SOFA, CFS and sex (Fig. ...