Immune cell densities in mature (mTLS) and immature tertiary lymphoid structures (iTLS). Upper left: Mean mTLS outer zone areas (mm2), T cell densities (cells/mm2) and intratumoral (IT) infiltration of single T cell and cyclinE1/cyclinD1/c-Myc IHC markers. BRCA mutation and HRD status are given when known, alongside progression-free interval (PFI, months). Upper right: Mean mTLS inner zone areas, B cell maturation and activation panel densities and IT infiltration of B cell IHC markers. Lower panels: Corresponding variables in iTLS depicting cell densities in iTLS. Single IHC IT immune infiltration and cyclins/c-Myc were dichotomized into high/low. * p = 0.0022 for PT vs pMet