Figure 2 - available via license: Creative Commons Attribution 3.0 Unported
Content may be subject to copyright.
Homeokinesis. The complex dynamic equilibrium of the body is possible thanks to interacting components found in plants, energo, orga and info ceuticals, as well as the negative entropy, information, provided by spiritual healing. The action of these components is necessary to offset aggressors. 

Homeokinesis. The complex dynamic equilibrium of the body is possible thanks to interacting components found in plants, energo, orga and info ceuticals, as well as the negative entropy, information, provided by spiritual healing. The action of these components is necessary to offset aggressors. 

Source publication
Article
Full-text available
Western medical science lacks a solid philosophical and theoretical approach to disease cognition and therapeutics. My first two articles provided a framework for a humane medicine based on Modern Biophysics. Its precepts encompass modern therapeutics and CAM. Modern Biophysics and its concepts are presently missing in medicine, whether orthodox or...

Context in source publication

Context 1
... Theory constitutes the philosophical and scientific foundation of Systemic Medicine. It establishes scientific, and ethical, boundaries for a more comprehensive and humane medicine. Its fundamental principles should be known and understood by all health care professionals, independent of their practice, be it orthodox or CAM. In brief, the survival potential or health response of any living system is given by its capacity to generate Energy, Intelligence and Organization. These three parameters—E, I, O—constitute the common denominator of life, and can be represented by a triangle, due to their synergetic interdependency. Enhancing the triangle’s components maximizes health. Reducing them, results in loss of health and eventual death. Moreover, given that chronic degenerative sickness is an outcome of higher systemic entropy, where cancer stems from surpassing a critical entropy level, the way to health requires that we induce negative entropy in patients (Fig. 1). Nature’s life fuel, found in many ‘nutraceuticals’ is composed of survival energy and information, necessary to enliven system’s intelligence and organization. Energy (1–9) and information (10) are thus the active principles of life, while negative entropy—healing—is the action mechanism that results. This lays foundations for the Golden Rules of Therapeutics (11,12). This new way of thinking, in biophysics (13), explains active principles and action mechanisms behind, millenary non-iatrogenic, energoinformational therapeutics. Examples include spiritual healing, kampo; traditional Chinese medicine, ayurveda, unani, etc. and more recently homeopathy and Western energy medicine. It also summons for a new understanding of placebo effect, since the common denominator to all healing is negative entropy. This requires a change of paradigm. As Ernst (14) points out ‘ . . . the placebo effect is an important contributor to the overall therapeutic effect, which should be cultivated rather than eliminated . . . ’ and also questions the ‘unethical use of placebo’ as described in the Declaration of Helsinki. The Systemic Theory is inclusive. It encompasses all medical practice since its laws and axioms are inherent to life. It paves the way to future therapeutics (Fig. 2). The function of the whole is tantemount to the individual action of its parts, due to synergy and emergence, inherent characteristics of all living systems (15). Thus, to simplify an organic failure to just one organ—or isolated biofeed- back mechanism—is an incomplete approach. Modern pharmacological therapeutics, based on reductionism, is non- organismic. It deviates from treating body, and spirit, as an integrated system; maybe this is why it has become increas- ingly dehumanized. Some regard traditional forms of healing as unscientific; however, in many ways some of these practices, based on a philosophical system’s approach, are less primitive more scientific (13) and humane than orthodox therapeutics. I do not challenge the precision of modern Western diagnoses which is nonpareil; however, I do question the use, in Western therapeutics, of many harmful drugs— replete in side effects—which are also mostly inefficient in the treatment of chronic degenerative diseases. Observing the extensive use of traditional healing systems in China, India, Indonesia and Japan, to mention a few instances, an impartial observer must acknowledge that there is more to these medicines than wishful thinking. Three billion people treated with holistic systems, with as much success as their Western coun- terparts compels respect even in the most incredulous (Fig. 3). Systemic Theory complements the core concepts of ‘far from equilibrium’, ‘self-organization’, autopoiesis, homeokinesis (16) and dissipative structures by introducing the missing parameters of the life equation: Intelligence and Survival. Without the latter none of the former phenomena would be possible in a living system. According to reasoning, organization, in ‘far from equilibrium’ systems simply cannot be reached and maintained, without a modulating intelligence and an adaptive energy generator within the system. Intelligence, to be understood, should be defined in terms of a scale of consciousness. In other words, it exists in a gradient scale of awareness, i.e. from the very aware to the unaware. One could propose that humans are conscious of being aware, while an ant or a plant is possibly aware only of its surroundings. Life presents a variable scale of consciousness. Thus, intelligence, the ‘subjective’ permeating substance—or field—that enlivens the physical universe, is the vital parameter that should be included in analyzing any system. It accounts for self-organization. Intelligence is the genesis, the causative entity, the central controller. General system theory’s (GST’s) postulate of ‘Self-Organization’ (17) is paradoxical and non sequitur , since it ignores biological and spiritual ‘Intelligence’. GST assumes ‘autopoiesis’ as a spontaneous phenomenon, excluding a central controller whether spiritual, biological, wavelike, field-form or of any origin. Intelligence, the coordi- nating entity, is thus missing in GST and also in artificial intelligence theory. This is the entity without which coordinated self-organization simply cannot occur. It is axiomatic. For any system to survive, there must exist at least one supraintelligence to synchronize each of the ‘lesser’ intelligences that regulate the subdivisions of the whole. This obvi- ously emergent intelligence enforces the survival goal to all of its lower echelons, unless it becomes deranged. For this reason, it can be assumed that all systems posses an increasing scale of contributive intelligence, from nano to macro systems. In synthesis, without intelligence there can be no living system. Empirical proof of this is chaos as the obverse, flip side, of Intelligence; i.e. Total Chaos 1⁄4 À I ad infinitum . Before undertaking the concept of Synergetics, and multiple bidirectional potential, the terms tonics and adaptogens must be described. According to Mowrey (18) a tonic is defined as ‘any substance that balances the biochemical and physiolo- gical events that comprise body systems’. Whereas the term ‘adaptogen’ introduced by Lasarev in 1947 defines ‘a substance of plant origin that is able to increase a non-specific resistance of the organism to stress factors and thereby pro- mote its adaptation to stressful external conditions’ (19). But what is synergetics? Synergetics, is the result of information exchange and survival decisions within the living system. It is a complex manifestation of Intelligence. Without Intelligence there can be no synergy. One form of this synergy, known as bidirectional adaptation (18), is triggered by tonic and adaptogenic herbs. Bidirectional adaptation can only be explained in terms of Intelligence. The informational entity perceives, differentiates, selects and utilizes active principles necessary to achieve homeokinesis in a ‘far from equilibrium’ system from a massive number of ‘ceuticals’ present in herbs and nutrients. Thus, ‘ . . . natural products provide a veritable cornucopia of sources of new CAM approaches that will emerge as ...

Similar publications

Article
Full-text available
ROMK ist ein einwärts-gleichrichtender Kaliumkanal, der hauptsächlich in der Niere exprimiert wird. Er wird dabei vor allem in der apikalen Membran des aufsteigenden Astes der Henleschen Schleife, dem distalen Tubulus und dem Sammelrohr exprimiert. Die Hauptaufgaben von ROMK bestehen in der Rezirkulation von Kalium im dicken aufsteigenden Ast der H...

Citations

... Systemic Theory postulates that health is directly proportional to the integrity of a living system's energy, bio-intelligence and organization Olalde & Rangel, 2005). Systemic Theory also establishes a common denominator to all sickness and attributes the cause of disease to be an increase in entropy: disorder augmenting within the biological system, stemming from energo-informational and organizational impacts. ...
Article
Full-text available
We propose the unification of two medical paradigms: Orthomolecular Medicine and Systemic Medicine with their mechanistic counterparts, Metabolic Correction and Physiological Modulation as tools to achieve the healthy state by attaining physiological optimization. In Western therapeutics, the use of drugs, which have many side effects and are often inefficient in the treatment of chronic degenerative diseases, is common. Observing the extensive use of traditional healing systems in China, India, Indonesia and Japan, an impartial observer must acknowledge that there is more to these medicines than just wishful thinking. Three billion people are treated with holistic medicines with much success; addressing the root cause of the physiologic disruption is key. Metabolic correction is a functional biochemical approach to improving cellular biochemistry by means of providing necessary cofactors and coenzymes that favor optimal physiological balance to attain and maintain the healthy state. Metabolic Correction is achieved by judicious hydration, nutritious food intake and scientific supplementation. In addition, identification of contaminants, endocrine disruptions and infections is necessary to properly address the underlying cause of disease.
... Non-ideal prescriptions perform by improving maybe a couple components, but concurrently destroy the residual one(s), leading to adverse effects [22]. Nevertheless, adaptogens activate bidirectional alteration by triggering and re-establishing the balance of all three factors in an ideal way [22,23]. Animals are exposed to the similar kind of stressor for diverse phases to induce CS experimentally. ...
Article
Full-text available
Background: Oxitard, a polyherbal formulation comprising the extracts of Withania somnifera, Mangifera indica, Glycyrrhiza glabra, Daucus carota, Vitis vinifera, powders of Syzygium aromaticum, Yashada bhasma and Emblica officinalis; and oils of Triticum sativum. Objective: Current study deals with the assessment of Oxitard (a marketed polyherbal formulation) for its adaptogenic potential in chronic unpredictable stress (CUS) and chronic stress (CS) induced dysfunctional homeostasis in rodents. Materials & methods: Animals were immobilized for 2 h every day for ten days to induce CS. In order to induce CUS, animals were employed in a battery of stressors of variable value and duration for ten days. Following administration of Oxitard, stress was induced in the animals. Stress-induced efficient changes were evaluated by assessing organ (adrenal gland) weights, ulcer index, hematological parameters and biochemical levels of reduced glutathione (GSH), thiobarbituric acid reactive substances (TBARS) and catalase (CAT). Results: CS and CUS significantly modified the oxidative stress parameters (increased MDA and decreased GSH). Furthermore, CS and CUS lead to weight reduction, adrenal hypertrophy and gastric ulceration. Pre-treatment with Oxitard (200 and 400 mg/kg, p.o.) significantly modified CS and CUS induced hematological changes, oxidative stress parameters and pathological effects. Conclusion: In conclusion, Oxitard-intervened antioxidant actions are accountable for its adaptogenic effects in stress-induced dysfunctional homeostasis.
... Estimulante de funciones cognitivas vinculadas a desórdenes neurodegenetarivos (Olalde Rangel 2005). Antidepresivo (Mamedov 2005). ...
Article
Full-text available
Recebido em agosto de 2015. Aceito em dezembro de 2015. Publicado em dezembro de 2015. ___________________________________________________________________________________________________________ RESUMEN – Este trabajo presenta resultados parciales de una línea de investigación en Etnobotánica urbana, desarrollada por el Laboratorio de Etnobotánica y Botánica Aplicada (LEBA) en el Área Metropolitana de Buenos Aires, Argentina. Se incluyen datos sobre 30 especies de plantas medicinales cuyos productos se comercializan como potenciadores cognitivos, vinculados con distintas condiciones neurológicas y psicológicas. Muchas de estas especies se emplean asimismo como adaptógenos. Se relevaron 145 sitios de expendio pertenecientes al circuito comercial general y al circuito restringido de dos segmentos de inmigrantes: boliviano y chino. Para cada especie se indican productos, muestras y usos asignados, con sus estudios de validación. La discusión contribuye a la comprensión de la complejidad del conocimiento botánico en los contextos pluriculturales urbanos, y a la dinámica de su transmisión sobre la base de la difusión de los productos relevados. PALABRAS CLAVE: Etnobotánica urbana, potenciadores cognitivos, adaptógenos, conocimiento botánico, Buenos Aires. ___________________________________________________________________________________________________________ THE BOTANICAL KNOWLEDGE IN URBAN AREAS: COGNITIVE ENHANCERS MARKETED IN THE METROPOLITAN AREA OF BUENOS AIRES, ARGENTINA ABSTRACT – This paper presents partial results of a research line on urban Ethnobotany, developed by the Laboratorio de Etnobotánica y Botánica Aplicada (LEBA) in the Metropolitan Area of Buenos Aires, Argentina. Data on 30 species of medicinal plants whose products are marketed as cognitive enhancers, linked to various neurological and psychological conditions are included. Many of these species are also used as adaptogens. 145 outlets belonging to general commercial circuit and the limited scope of two segments of immigrants (Bolivian and Chinese) were surveyed. Products, samples and assigned uses (with studies that validate them), are indicated for each species. The discussion contributes to the understanding of the botanical knowledge complexity in multicultural urban contexts and the dynamics of its transmission based on the diffusion of the products surveyed. KEY WORDS: Urban ethnobotany, cognitive enhancers, adaptogens, botanical knowledge, Buenos Aires. ___________________________________________________________________________________________________________ O CONHECIMENTO BOTÂNICO EM ÁREAS URBANAS: ESTIMULADORES COGNITIVOS COMERCIALIZADOS NA ÁREA METROPOLITANA DE BUENOS AIRES, ARGENTINA RESUMO-Este artigo apresenta resultados parciais de uma pesquisa em Etnobotânica urbana, desenvolvida pelo Laboratorio de Etnobotánica y Botánica Aplicada (LEBA) na Área Metropolitana de Buenos Aires, Argentina. São apresentados dados sobre 30 espécies de plantas medicinais, cujos produtos são comercializados como estimuladores cognitivos, ligados a várias condições neurológicas e psicológicas. Muitas destas espécies também são consumidas como adaptógenos. Cento e quarenta e cinco pontos de venda foram pesquisados, pertencentes ao circuito comercial geral e ao circuito restrito de dois grupos de imigrantes: bolivianos e chineses. Para cada espécie são indicados: produtos, amostras, e usos atribuídos com seus estudos de validação. A discussão ajuda a compreender a complexidade do conhecimento botânico em contextos multiculturais urbanos, e sua dinâmica de transmissão com base na difusão dos produtos pesquisados.
... The medication using medicinal plants uses holistic approach by investigating the disease up to the main origin causing the unbalancing and deficiency in the body function (Cracker & Giblette, 2002). The whole body functions caused by the synergy and the existence of individual actions from body parts are the characteristics of living creatures therefore the reductionist view of the disease concept, that just blames an organ or a certain isolated mechanism, is an incomplete approach (Rangel, 2005). ...
Article
Full-text available
p>Medicinal plants have been a revolutionary breakthrough in the treatment of male sexual dysfunction. Traditional medicine based on a holistic philosophy is quite different with the practice of “western” medicine. Phytochemical substances focus their mechanisms of healing to the root of cause, i.e. the inability of controlling the proper function of the whole body system. Hence, medicinal plants manage sexual dysfunction and male fertility in the frame of sexual dysfunction as a whole entity. Some previous researches prove that the use of medicinal plants have a good impact in the treatment of a variety of male sexual problems. This paper will discuss several important aspects of aphrodisiac plants and preliminary study regarding them in Indonesia. Difficulties inherent to activity guided isolation and the specific requirements of bioassays are also discussed.</p
... In the second year of eCAM, I agreed to assist Jose Olalde Rangel to publish his treatise. According to Olalde Rangel (2)(3)(4)(5), the systemic theory postulates that health (H) is directly proportional to the integrity of a living system's energy (E), biointelligence (I) and organization (O). Systemic theory also establishes a common denominator to all sickness and ascertains the cause of all disease to be an entropy increase: 'disorder augmenting within the biologically open system, stemming from energy-informational and organizational impacts, either of external or internal nature. ...
Article
Full-text available
Sasang Constitutional Medicine (SCM), also referred to as 'integrative medicine', constitutes a unique contribu- tion to the growing field of complementary and alterna- tive medicine. Like all other ancient cultures—including those from India, (Ayurveda) China (TCM), Japan (Kampo), Korea (TKM) and the Mediterranean (TAIM)—there is an emerging fascination with, and indeed use of, these approaches as adjuncts to Western medicine and often as alternatives. This special supple- ment to eCAM represents a milestone, in that it is the first publication in this area of alternative medical prac- tices to be published. The papers were first written and subjected to internal peer review by scientists at the Korea Institute of Oriental Medicine in Daejeon, Korea (KIOM). The very best papers were then chosen and submitted by the usual route to eCAM. They were then subjected to further intense international peer review and underwent revisions based upon the referees' comments. What is presented here consists of the very best papers that survived the internal KIOM review process as well as the scrutiny of the anonymous referees and members of the editorial board of eCAM. In keeping with the tradition of eCAM, for each pub- lication there was a strong effort to present information in clear English, often requiring the certification of a licensed expert familiar with transparent and scientific English, followed by the necessity to impose certain sty- listic suggestions to improve the appearance and general readability of papers. In all instances, authors were urged to consider supplementing the text with appropriate hypothetical drawings that best explain newly presented results and propose future approaches to validate certain claims. This not only helps authors, but it also provides clarity for readers and useful information important in teaching and for presentation at various meetings. The entire supplement is organized and presented as Reviews and Original Articles of two types: Basic Science and Clinical Analyses, the usual style of eCAM. The introductory paper contributed by Prof. Denis Noble sets the stage for the entire supplement. In his words, '(a)ttitudes towards oriental medicine are changing for two major reasons. First, many patients, even in the West, are choosing to use its practitioners and methods. Second, the rise of oriental and Western traditions; much work is required to facilitate dialogue and synthesis. There should be time devoted to clarifying meanings of terms and the framework of theory and practice within which oriental methods operate. Moreover it is necessary for Systems Biology just emerging itself to mature as a discipline, particularly at the higher levels of biological organization since it is at these levels that oriental medi- cine derives its ideas and practice. Higher level Systems Biology could then be a basis for interpreting the Korean version of oriental medicine: Sasang constitutional medi- cine since it seeks patient specific analysis and treatment, and the mathematical methods of systems biology could be used to analyze the central concept of balance in Sasang.'
... From the results of this experiment, it was evident that of all the dose level employed, HK produced significant reduction in number and time spent in itching, suggesting that HK has potent antipruritic activity probably mediated by mast cell stabilization along with 5-HT antagonism. On the whole, the antiallergic property of HK could be attributed to the presence of immunomodulatory herbs such as A. chinensis (3), O. sanctum (4), P. longum (5) and antiallergic herbs such as B. monniera (31) and P. longum (32) used in the formulation, which further strengthens the concept of synergistic healing potential of polyherbal formulations (33). ...
Article
Full-text available
Herbex-kid (HK), a polyherbal formulation was evaluated in various experimental allergic models of Type I hypersensitivity reactions. Compound 48/80 (C 48/80) has been shown to induce rat mesentery mast cell degranulation and HK (1.07, 10.75 and 107.5 mg ml(-1)) inhibited the mast cell degranulation in a dose dependent manner. HK (1.07, 10.75 and 107.5 mg kg(-1); p.o.) showed dose-dependent protection against C 48/80 induced systemic anaphylaxis in male Balb/C mice. In active anaphylaxis model, male Wistar rats orally administered with 10.75 and 107.5 mg kg(-1) of HK showed significant (P < 0.01) protection against mast cell degranulation, while in passive anaphylaxis model, only at 107.5 mg kg(-1) showed significant (P < 0.01) reduction in mast cell degranulation. HK at all dose levels was able to significantly decrease the time spent in nasal rubbing in Wistar rats sensitized to ovalbumin, while only at 107.5 mg kg(-1) it showed significant (P < 0.01) reduction in number of sneezes. In C 48/80-induced skin itch model, all dose levels of HK significantly (P < 0.001) decreased the time spent in itching and the number of itches. HK did not produce any significant inhibition in histamine induced contraction in guinea pig ileum. From the above findings we conclude that the HK possesses antiallergic activity mediated by reducing of the release mediators from mast cells and also by 5-HT antagonism without the involvement of histamine (H1) receptors.
... Scott-Morley, personal communication) that the electric potentials they detect in the acupuncture meridians/nadis, originate in standard transmembrane potentials of body cells-in other words, they are a Vata phenomenon. Finally, of the three doshas, Vata is the closest to being active intelligence (it is the 'intelligence' aspect of systemic medicine), and thus to subjective awareness (15)(16)(17)(18). ...
Article
Full-text available
Many CAM modalities afford relief from pain, each in its own way, or according to its own terminology. Comparison of different CAM modalities results in a simple phenomenology of pain centered around the idea that pain may be associated with blockages of the flow of energy in the system of nadis/acupuncture meridians.
... This area may seem far from the clinical work implied by the title of our journal, yet as a biologist I see this as laying the foundation for new and exciting products that will eventually make their way into the clinical arena. At the same time, though, we have kept our commitment to the orientation of medicine and have included some true clinical papers that are theoretical (2)(3)(4)(5), practical and even some that are based upon readily applicable and easily recognized animal models (6,7). Now our journal deems it essential to embark on a more rigorous and concerted tact broadening our 2 year attempts to recruit, review and publish high quality papers that are clinical. ...
Article
Full-text available
... Systemic Theory postulates that Health (H) is directly proportional to the integrity of a living system's Energy (E), Bio-Intelligence (I) and Organization (O) as shown in Fig. 1. Systemic Theory also establishes a common denominator to all sickness (Fig. 2) and ascertains the cause of all disease to be an entropy increase: 'disorder augmenting within the biologically open system, stemming from energo-informational and organizational impacts, either of external or internal nature' (9)(10)(11). Therapeutics should then include a negentropy supply to enhance the system's energy-work capacity (E), its informational potential (I) intelligence, and finally structure and functional organization (O). ...
... Healing potential, negentropy gain, is directly proportional to synergetic contribution (SC) (11). SC is exponentially proportional to the number of contributive active principles (n) in a formula-ergo in a protocol. ...
Article
Full-text available
This fourth lecture illustrates the praxis and results of Systemic Medicine (SM) in various therapeutic applications. SM's success has made it popular throughout Venezuela and Puerto Rico. The treatment of over 300,000 patients by 150 orthodox MD's, trained and qualified in SM, in 35 medical establishments with above average results corroborate its effectiveness as an eCAM in chronic degenerative diseases. Herein we provide a synopsis of results obtained in four such pathologies-the journal's necessary space restrictions somewhat limiting content-as well as clinical and photographic evidence. The validity of any medical theory is substantiated by its degree of effectivity and success. The workability of evidence-based SM corroborates Systemic Theory's transcendence.