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Figure 1 - A census of cell types and paracrine interactions in colorectal cancer

Figure 1: Generation and initial assignment of CRC single-cell RNA sequencing data. A Clinical data for the eight patients under investigation in this study. For mutational data, see also Supplementary table 6. Loc (Localisation): C: cecum; S: sigmoid colon; T: transverse colon; A: ascending colon; R: rectum. Prog (Predicted Progression): S: via serrated precursor; I: inflammatory/colitis-associated; C: canonical. Tissues used for single-cell RNA sequencing: N: Normal; T: Tumor; O: Organoid. B UMAPs of epithelial, immune and stromal cells, color-coded for patients. C UMAPs of epithelial, immune and stromal cells, color-coded by tissue of origin.
Generation and initial assignment of CRC single-cell RNA sequencing data. A Clinical data for the eight patients under investigation in this study. For mutational data, see also Supplementary table 6. Loc (Localisation): C: cecum; S: sigmoid colon; T: transverse colon; A: ascending colon; R: rectum. Prog (Predicted Progression): S: via serrated precursor; I: inflammatory/colitis-associated; C: canonical. Tissues used for single-cell RNA sequencing: N: Normal; T: Tumor; O: Organoid. B UMAPs of epithelial, immune and stromal cells, color-coded for patients. C UMAPs of epithelial, immune and stromal cells, color-coded by tissue of origin.
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