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Flowchart delineating the inclusion of patients with CRE sepsis following ERCP. Abbreviations: ERCP, Endoscopic retrograde cholangiopancreatography; CRE, Carbapenem-resistant Enterobacterales

Flowchart delineating the inclusion of patients with CRE sepsis following ERCP. Abbreviations: ERCP, Endoscopic retrograde cholangiopancreatography; CRE, Carbapenem-resistant Enterobacterales

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Flowchart delineating the inclusion of patients with CRE sepsis...
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Carbapenem-resistant Enterobacterales sepsis following endoscopic retrograde cholangiopancreatography: risk factors for 30-day all-cause mortality and the development of a nomogram based on a retrospective cohort
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  • Aug 2024
Background Endoscopic retrograde cholangiopancreatography (ERCP) has become a routine endoscopic procedure that is essential for diagnosing and managing various conditions, including gallstone extraction and the treatment of bile duct and pancreatic tumors. Despite its efficacy, post-ERCP infections – particularly those caused by carbapenem-resista...
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... This case presents an unusual occurrence of TLS triggered by ERCP, a procedure commonly performed for biliary decompression. TLS, in this context, is believed to result from the physical manipulation of the tumor and the release of intracellular components, including potassium, phosphate, and uric acid, into the bloodstream [8]. This metabolic surge overwhelms the kidneys' ability to excrete these substances, leading to acute kidney injury (AKI), hyperkalemia, hyperphosphatemia, hyperuricemia, and secondary hypocalcemia caused by phosphate precipitation with calcium [9]. ...
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