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INTRODUCTION
Work simplification is scientific approach to study work processes with
view to simplifying the process such that the work process becomes
more efficient and effective thereby raises productivity and reduces
wastage of labor effort, material, space, time & energy in the process of
producing a good or delivering a service. Work simplifi...
Citations
Human beings square measure in shut relation with the microorganisms that was common in nature. Immune system could be a means that of protection against the damaging effects of noxas, that cause infection in our bodies. The immune response by humans to CoV-2 virus occurs which is a combination of the cell-mediated immunity and antibody production, just as with most other infections. There are limited proven on therapeutic options for the prevention and treatment of COVID-19. The role of vitamin and mineral supplementation or “immunonutrition” has previously been discovered in a number of clinical trials in rigorous care settings and there are several hypotheses which were support their routine use. The aim of this book chapter was to investigate whether vitamin supplementation is beneficial in COVID-19. This book chapter summarizes the immunemediating, antioxidant and antimicrobial activity of vitamins A to E which were explored and their potential role in the immune function that fight against COVID-19 was evaluated. The major topics mined for narrative synthesis were physiological and immunological roles of each vitamin and their role in respiratory infections, acute respiratory distress syndrome (ARDS) and also COVID-19. Vitamins A to E was highlighted because of their potentially beneficial roles in the fight against COVID-19 via antioxidant effects, immunomodulation, enhancing natural barriers and local paracrine signaling. Level 1 and 2 evidence showed the use of thiamine, vitamin C, and vitamin D in COVID-19 such as respiratory diseases, ARDS, and sepsis. While there are currently no published clinical trials due to the novelty of SARS-CoV-2 infection, there is pathophysiologic rationale for exploring the use of vitamins in this global pandemic, which is supported by early anecdotal reports from international groups. The final outcomes of ongoing trials of vitamin supplementation are looked-for with in interest.