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![Extracted ion chromatograms (left, from targeted single ion monitoring [tSIM]) showing a sample from a diabetic patient after administration (regular treatment) of the fast‐acting synthetic insulin aspart and the long‐acting insulin detemir. Mass spectra (right) of insulin aspart (SIM, top), showing 5‐fold protonated precursor ion and of insulin detemir (ddMS2, bottom) with two diagnostic product ions including the attached myristic fatty acid](profile/Sam-Thilmany/publication/362850873/figure/fig3/AS:11431281113568808@1673978667534/Extracted-ion-chromatograms-left-from-targeted-single-ion-monitoring-tSIM-showing-a.png)
Extracted ion chromatograms (left, from targeted single ion monitoring [tSIM]) showing a sample from a diabetic patient after administration (regular treatment) of the fast‐acting synthetic insulin aspart and the long‐acting insulin detemir. Mass spectra (right) of insulin aspart (SIM, top), showing 5‐fold protonated precursor ion and of insulin detemir (ddMS2, bottom) with two diagnostic product ions including the attached myristic fatty acid
Source publication
Bioactive peptides with a molecular mass between 2 and 10 kDa represent an important class of substances banned in elite sports, which has been recognized with an increasing number and variety of substances by anti-doping organizations. Also, the annually renewed list of prohibited substances of the World Anti-Doping Agency (WADA) explicitly mentio...
