Evolution of skin wrinkle parameters by skin biophysics analysis after 28 days of using test or control products. (a) Mean changes in SEw (mean ± SD). (b) Mean changes in SEsm (mean ± SD). Data were analyzed using the Friedman test; *p < 0.05, compared with the baseline. SD, standard deviation.

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Continuous Skin Rejuvenation by Combining Nonablative Fractional Laser With Daily Application of a Multibeneficial Composition Formulation: A Blinded Randomized Clinical Trial Study

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Full-text available

Mar 2025

Xinxuan Zhang
Manru Ning
Mengqing Lin
[...]
Xiaoke Xu

Background and Aims Skin aging is a common concern among individuals, and laser treatments are recognized as one of the most effective approaches to mitigate the aging process. The study aims to compare a multibeneficial formula serum versus a blank formulation in achieving maximum efficacy following a single treatment of nonablative fractional las...