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Some patients with medically refractory focal epilepsy are chronically implanted with a brain-responsive neurostimulation device (the RNS ® System), permitting neurophysiological measurements at millisecond resolution. This clinical device can be adapted to measure hippocampal dynamics time-locked to cognitive tasks. We illustrate the technique wit...
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... surgical patients, several electrodes may be placed in the hippocampus, however, as similar visual association tasks have shown robust activation within anterior regions of the hippocampus 15-18 , we selected the electrode pair with the best signal quality located in the anterior hippocampus. The electrode selection for each patient is provided in Table 2. . CC-BY-NC-ND 4.0 International license a certified by peer review) is the author/funder, who has granted bioRxiv a license to display the preprint in perpetuity. ...Similar publications
Epilepsy associated with Rasmussen’s encephalitis (RE) is highly resistant to standard therapy and continues to present a therapeutic challenge. While epilepsy surgery remains the most effective management for patients with drug-resistant focal epilepsy and RE, hemispherotomy may debilitating consequences on adult patients. Here we present the outc...
