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Effect of magnolol derivatives on lipofuscin levels in wild-type C. elegans. (A–L) Relative fluorescence intensity of lipofuscin accumulation in C. elegans after treatment with magnolol derivatives. n = 60, x‾ ± s. *p < 0.05, **p < 0.01, ***p < 0.001 ****p < 0.0001.
Source publication
Magnolol (M), a hydroquinone containing an allyl side chain, is one of the major active components of Houpoea officinalis for antioxidation and anti-aging. To enhance the antioxidant activity of magnolol, the different sites of magnolol were structurally modified in this experiment, and a total of 12 magnolol derivatives were obtained. Based on the...
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