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Effect of coconut water on sperm count for 10, 20, and 30 days of treatment Results are presented as mean values of five rats. Bars with different letters are significantly different at p<0.05
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Background: The need for fertility stimulation in men and women cannot be overemphasized especially when a marriage is childless in some communities in Nigeria. While chemical methods for fertility stimulation may have some side effects and are not readily available, remedy from natural sources can be used. Aim: This present study is aimed to evalu...
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Healthy and superior sperm is the main requirement for a woman to get pregnant. To find out how the quality of sperm is needed several checks. One of them is a sperm analysis test to see the movement of sperm objects, the analysis is observed using a microscope and calculated manually. The first step in analyzing the scheme is detecting and separat...
Citations
... Despite Nigeria having a high fertility rate [23], infertility is still widespread and varies by ethnic group. Infertility is the failure of a couple to conceive within a year of regular, unprotected sexual intercourse [35,36]. ...
... Male infertility, which has about 30% global incidence rate and is thought to account for 50% of the world's cases directly, is recently gaining international attention [1]. It has been difficult to comprehend the prevalence and nature of male infertility throughout Africa due 15 to a paucity of statistics and the fact that African males rarely submit to fertility testing and typically hold women responsible for the bulk of infertility cases in the family [2]. ...
... The high consumption of coconut by males could be due to the presence of vitamin E, selenium, fibre and manganese, which improve men's sexual health [18]. Research shows that coconut water could enhance reproductive functions by increasing testosterone levels and subsequently affecting fertility in males [19]. Another reason for the high consumption by males could be the 'satisfying' nature of the mesocarp (fleshy middle layer). ...
... Plant components are essential to conventional and medical procedures and have continued to be good sources of novel medications (Airaodion et al., 2019i). Alternative healthcare is still used throughout the world, despite the fact that mainstream medical therapy is generally becoming acceptable (Ogbuagu et al., 2019). ...
Tel.: +2347030204212 Corchorus protect the liver from hepatotoxicity that has been expe The purpose of this study potential olitorius and Training, Moor Plantation, Nigeria. They were extracted using a technique with 95% ethanol as the solvent. Twenty were used in the experiment. Before the experiment began, they were given seven (7) days to get acclimated to a laboratory setting. At random, they were split up into groups A, group and received oral distilled water. Animals in groups C and D received C. olitorius addition to the 100 mg/kg body weight of potassium bromate given groups B, C, and D. Every day for 28 days, prepared potassium bromate were given orally to rats. The animals were sacrificed and blood and liver tissue were collected for the determination of hepatic biomarkers. control group, KBrO LDH, ALP, total bilirubin (TB), conjugated bilirubin (CB), and unconjugated bilirubin (UB) levels, but decreased total protein, albumin a serum of animals. In the liver cells, KBrO These perturbations were neutralized in the groups treated with 100 and 200 mg/kg of study, potassium bromate caused liver injury by unhinging important hepatic indicators. Increased efforts should be made to stop the use of potassium bromate in food processing. Furthermore, by bringing the examined biomarkers back in the control group of animals, it may be inferred that have a significant hepatoprotective effect against liver damage caused by potassium bromate. We recommend consumption of this Abstract Corchorus olitorius leaves have been reported to possess the ability to protect the liver from hepatotoxicity that has been expe he purpose of this study therefore was to investigate its hepatoprotective potential against potassium bromate-induced hepatot olitorius (jute) plants were taken from the Institute of Agricultural Research and Training, Moor Plantation, Nigeria. They were extracted using a technique with 95% ethanol as the solvent. Twenty were used in the experiment. Before the experiment began, they were given seven (7) days to get acclimated to a laboratory setting. At random, they were split up into groups A, B, C, and D. Group A served as the control group and received oral distilled water. Animals in groups C and D received C. olitorius at doses of 100 and 200 mg/kg body weight, respectively, in addition to the 100 mg/kg body weight of potassium bromate given groups B, C, and D. Every day for 28 days, C. olitorius prepared potassium bromate were given orally to rats. The animals were sacrificed and blood and liver tissue were collected for the determination of hepatic biomarkers. The findings demonstrated that, when compared to the control group, KBrO 3 caused a significant increase (LDH, ALP, total bilirubin (TB), conjugated bilirubin (CB), and unconjugated bilirubin (UB) levels, but decreased total protein, albumin a serum of animals. In the liver cells, KBrO 3 reduced hepatic biomarkers. These perturbations were neutralized in the groups treated with 100 and 200 mg/kg of C.olitorius body weight respectively. According to the current study, potassium bromate caused liver injury by unhinging important hepatic indicators. Increased efforts should be made to stop the use of potassium bromate in food processing. Furthermore, by bringing the examined biomarkers back to levels that are substantially identical to those in the control group of animals, it may be inferred that have a significant hepatoprotective effect against liver damage caused by potassium bromate. We recommend consumption of this leaves have been reported to possess the ability to protect the liver from hepatotoxicity that has been experimentally induced. was to investigate its hepatoprotective induced hepatotoxicity. Fresh C. (jute) plants were taken from the Institute of Agricultural Research and Training, Moor Plantation, Nigeria. They were extracted using a Soxhlet technique with 95% ethanol as the solvent. Twenty-four male Wistar rats were used in the experiment. Before the experiment began, they were given seven (7) days to get acclimated to a laboratory setting. At random, they B, C, and D. Group A served as the control group and received oral distilled water. Animals in groups C and D received at doses of 100 and 200 mg/kg body weight, respectively, in addition to the 100 mg/kg body weight of potassium bromate given to C. olitorius extract and freshly prepared potassium bromate were given orally to rats. The animals were sacrificed and blood and liver tissue were collected for the determination of dings demonstrated that, when compared to the caused a significant increase (P˂0.05) in ALT, AST, LDH, ALP, total bilirubin (TB), conjugated bilirubin (CB), and unconjugated bilirubin (UB) levels, but decreased total protein, albumin and globulin in the reduced hepatic biomarkers. These perturbations were neutralized in the groups treated with 100 and 200 According to the current study, potassium bromate caused liver injury by unhinging important hepatic indicators. Increased efforts should be made to stop the use of potassium bromate in food processing. Furthermore, by bringing the to levels that are substantially identical to those in the control group of animals, it may be inferred that C. olitorius leaves have a significant hepatoprotective effect against liver damage caused by potassium bromate. We recommend consumption of this vegetable. epatoprotective potential, Hepatotoxicity,
... With a global incidence rate of about 30%, infertility among males is fast becoming a matter of global concern with males reported to be directly involved in about 50% of global infertility prevalence [1]. Due to a lack of data and the fact that African men seldom consent to fertility testing and typically prefer to hold women accountable for the majority of infertility cases in the family, it has been challenging to understand the frequency and nature of male infertility across Africa [2]. ...
Background: Effects of various extracts of Corchorus olitorius leaves have been reported. In order to learn more about the extent to
... In many nations around the world, male infertility is steadily rising [1,2]. Infertility among men has reportedly increased to 12% in the USA, according to Louis et al. [3]. ...
Background: Parkia biglobosa seed has been reported to enhance sperm quality. Thus, this study sought to assess its ability in attenuating KBrO3-induced sperm abnormalities. Methodology: P. biglobosa was extracted with soxhlet extractor with 95% ethanol as the solvent. Twenty-four adult male Wistar rats were acclimatized under laboratory conditions and were randomly grouped into A, B, C and D. Group A was given distilled water orally. Animals in groups B, C and D were administered 100 mg/kg body weight of potassium bromate, but groups C and D were also treated with 100 and 200 mg/kg body weight of P. biglobosa respectively. Both potassium bromate and P. biglobosa were freshly prepared on daily basis and administered to rats by oral gavage. After 28 days of treatment, the animals were sacrificed under mild diethyl ether anaesthetization 24 hours after cessation of the last treatment. The cauda epididymis were separated from both testes and tinged with 2 mL of normal saline then teased. The suspension was mixed through a metallic net to avoid any other tissue contamination. This suspension was used for the determination of the sperm parameters. Results: Exposure of animals to 100 mg/kg body weight of KBrO3 significantly reduced sperm count, sperm motility, sperm viability and seminal pH but elevated sperm morphology when compared with animals in the control group at p<0.05. These perturbations were attenuated by 100 and 200 mg/kg body weight of P. biglobosa seed extract in a dose-dependent manner. Conclusion: The result of this study showed that potassium bromate induced abnormalities in sperm cells of treated animals, and seed extract of P. biglobosa attenuated these abnormalities in a dose-dependent manner. This pharmacological study is a useful tool for further drug development from the natural plant products.
... Coconut has been said to possess different kinds of beneficial properties such as vitamins, sugar, protein, electrolytes, minerals, dietary fibres, antioxidants, cytokins e.t.c, and has been particularly demonstrated in human's health 17 . However, little information is available on the pathological point of view and particular as it is often used for fertility purposes while undermining a potential harm to internal male genitalia. ...
Background:
Cocos nucifera (Coconut, Arecaceae family) is consumed as dietary fruit but little is known of it as sex enhancer.
Objective:
To investigate male sex hormones and copulation behavior indices in male Wistar rats administered husks extract.
Materials and methods:
Rats were grouped into control A, and treatment B to E (n=4); and administered husks extract at varying doses: 125mg/kg, 250mg/kg, 375mg/kg and 500mg/kg for 48days by oral intubation. Copulation behavior was assessed by introducing female rats to males (1:1) in a rectangular Plexiglas chamber and monitored by veterinary Anatomists. Blood samples for male sex hormones were collected and assayed by ELISA method.
Results:
Copulation behavior (500mg/kg treatment): mounting (9.66±0.79 to 29.08±2.16), ejaculation (7.66±0.38 to 16.93±0.76), intromission (22.01±1.67 to 38.11±3.35) frequencies, and ejaculation latency (7.92±0.43 to 12.28±0.41) increased remarkably (Group E). Correspondingly, mounting (133.31±1.18 to 93.39±0.43) and, intromission (88.13±3.12 to 74.55±1.19) latencies; post-ejaculation (3.16±0.14 to 2.18±0.34), inter-intromission (19.48±0.26 to 14.32±1.65) intervals reduced significantly (P≤0.05). Testosterone levels (Group E) increased: 3.82±0.6ng/dL to 5.14±0.3ng/dL while, LH and FSH values reduced: 2.92±0.6IU/L to 2.13±0.3IU/L and 2.28±0.7IU/L to 1.58±0.3IU/L significantly (p ≤ 0.05) while changes were dose-related.
Conclusion:
C. nucifera husks extract improves sexuality indices by regulating male sex hormones in male Wistar rats.
... About 15% of couples experience infertility as a health issue worldwide [1]. It is now clear that poor semen quality causes the issue in at least 50% of all cases [2,3]. Low sperm count is one of the recognized causes of infertility and may be brought on by hormonal imbalance caused by oxidative stress. ...
Aim: This study was aimed at assessing the therapeutic potential of Parkia biglobosa (P. biglobosa) seed against potassium bromate-induced testicular toxicity. Methodology: P. biglobosa was extracted with soxhlet extractor with ethanol as the solvent. Twenty-four adult male Wistar rats were acclimatized under laboratory conditions and were randomly grouped into A, B, C and D. Group A was given distilled water orally. Animals in groups B, C and D were administered 100 mg/kg body weight of potassium bromate, but groups C and D were also treated with 100 and 200 mg/kg body weight of P. biglobosa respectively. Both potassium Original Research Article Ezirim et al.; IJRRGY, 5(3): 78-89, 2022; Article no.IJRRGY.89786 79 bromate and P. biglobosa were freshly prepared on daily basis and administered to rats by oral gavage. After 28 days of treatment, the animals were sacrificed under mild diethyl ether anaesthetization 24 hours after cessation of last treatment. The testes were removed homogenized in the ice cold 0.25 M sucrose solution. The homogenates were centrifuged at 5000 ×g for 10 minutes in a refrigerated centrifuge. The supernatant was collected and stored frozen for further analysis. The parameters were measured using standard methods. Results: When compared to animals in the control group, animals intoxicated with KBrO 3 had lower testicular concentrations of total cholesterol, total protein, glycogen, sialic acid, MDA, and GSH, as well as higher levels of ALP, SOD, and CAT activity. Additionally, it was shown that as compared to the animals in the control group, KBrO 3 boosted the testicular ACP's activity. However, P. biglobosa treatment of intoxicated rats reduced these alterations in a dose-dependent manner. Conclusion: The results of this investigation demonstrated that potassium bromate caused testicular toxicity, and that P. biglobosa treatment counteracted this effect. Thus, it is recommended that these results be investigated in clinical trials in human volunteers.
... This causes suppression of energy metabolism. If ATPase activity is decreased, it could suppress the motility rate of sperm, as ATP is the main energy source of sperm and it is directly related to sperm motility [44]. Ogbuagu et al. [45] recently reported that ethanolic extract of Xylopia aethiopica fruit induced oxidative stress in Wistar rats. ...
Aim: This study was designed to assess the effect of Xylopia aethiopica fruit on the sperm qualities of male Wistar rats. Methodology: The fruits of Xylopia aethiopica were air-dried and extracted by Soxhlet extractor using ethanolic as solvent. The median lethal dose (LD 50) of the extract was assessed using standard method. Thirty adult Wistar rats were divided into five groups of six rats each. Animals in groups 1, 2, 3, and 4 were treated with 130, 259, 389 and 518 mg/kg body weight of X. aethiopica fruit extract respectively, while those in group 5 received normal animal feeds and water only. The administration was done once daily for 28 days via oral route. At the end of 28 days treatment, animals were sacrificed under ether anaesthesia in a desiccator after an overnight fast. The cauda epididymis were separated from both testes and tinged with 2 mL of normal saline then teased the cauda epididymis of each rat. The suspension was mixed through a metallic net to avoid any other tissue contamination. This suspension was used for the determination of the sperm parameters. Original Research Article Ogbuagu et al.; IJRRGY, 5(2): 44-55, 2022; Article no.IJRRGY.85714 45 Results: Ethanolic extract of Xylopia aethiopica fruit was observed to significantly perturbed sperm parameters of animals after 28 days of treatment. Sperm count and motility were significantly reduced by Xylopia aethiopica fruit in a dose-dependent manner when compared with those of the control group (P<0.05). Administration of Xylopia aethiopica fruit increased sperm mortality and abnormality when compared with the control animals (P<0.05). Seminal pH was decreased by ethanolic extract of Xylopia aethiopica fruit administration when compared with those in control animals (P<0.05). Conclusion: The findings of this study revealed that ethanolic extract of Xylopia aethiopica fruit adversely perturbed sperm quality of Wistar rats. This might not automatically translate to same effect in human. However, men interested in child-bearing should minimize its consumption.
... Plants like coconuts, have been used for many studies arising from heart diseases, stress reduction, antioxidant, and source of hydration, kidney stone prevention and reduction of blood pressure. Most recently, the water of immature coconut has been associated with fertility by increasing sperm motility and count (Augustine A. et al., 2019), but no substantial work has been done in consumption of coconut meat which contain the coconut oil and milk. Considering studies done in 2019, the consumption of coconut has increased in Nigeria by over 500% in the past five years (m-guardian-ng.cdn.ampproject.org/2019) ...
The comparative effects of Virgin Coconut oil (CocosNucifera) and
Coconut milk on fertility using male rats as model was studied. A total of 72 rats (40
adults male and 32 female) weighing between 200-250g were used in this study. Group 1
served as the control and received distilled water only. Group 2-4 were the test groups
and were fed orally with the coconut extracts. Group 2 was fed with virgin coconut oil
(VCO), group 3 fed coconut milk (CM) while group 4 was fed the mixture of coconut oil
and coconut milk. The animals at the end of a given duration respectively were
sacrificed and their semen sample were collected for sperm analysis. The result of the
study showed that the administration of Cocos Nucifera(VCO and CM) extracts
significantly decrease (p<0.05) the sperm count of the rat when compared with the
control. The virgin coconut oil (VCO) showed a further decrease (P<0.05) when
compared with coconut milk and mixture of coconut milk and VCO. Furthermore, there
was no significant difference from (CM +VCO) when compared with the control
(P>0.05). Also, the results showed that the sperm motility in rats treated with VCO, CM
and mixture of VCO + CM showed no significant difference on the immotile sperm
when compared with the control. VCO showed a significant decrease (P<0.05) on the
motile sperm followed by CM when compared with the control. The administration of
Virgin Coconut oil could have deleterious effect on fertility by significantly reducing the
motility of the sperm and reducing sperm count as well.
KEYWORDS: Virgin coconut oil, coconut milk, sperm count, sperm motility.
