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Effect of administration of ethanolic leaf extract of A. mexicana on superoxide dismutase activity in the stomach and duodenum of indomethacin-induced ulcerated rats. Values are mean of six determinations AE SEM. Bars with different alphabets are significantly different (p < 0.05) from each other. SEM, standard error of mean.

Effect of administration of ethanolic leaf extract of A. mexicana on superoxide dismutase activity in the stomach and duodenum of indomethacin-induced ulcerated rats. Values are mean of six determinations AE SEM. Bars with different alphabets are significantly different (p < 0.05) from each other. SEM, standard error of mean.

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Argemone mexicana (A. mexicana) is a plant traditionally used in Nigeria and some African countries to treat peptic ulcer disease. In this study, the ameliorative effect of ethanolic leaf extract of A. mexicana in indomethacin-induced peptic ulcer and its safety were investigated. Phytochemical screening was performed using standard procedures. Ulc...