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Background: The World Health Organization is encouraging the use of traditional medicinal plants through herbal formulations in countries around the world. Aim: The present investigation was focused on the development and stability study of polyherbal suspension produced from alcoholic extracts of selected medicinal plants. Methods: Four suspension...
Andrographolide (1) is a labdane type diterpene lactone abundant in the leaves of Andrographis paniculata . To further explore the stability of this important metabolite, the thermal degradation kinetics of 1 at pH values pH 2.0, pH 6.0, and pH 8.0 were each modeled at three temperatures ranging between 50 and 85°C. The calculated values of the act...
Andrographolide, a bicyclic diterpene from Andrographis paniculata is of immense pharmaceutical importance. A. paniculata, an annual herb from Acanthaceae is widespread in the Indian subcontinent. Heavy metals act as abiotic elicitors. The study deals with the effect of mercury (Hg), cadmium (Cd) and arsenic (As) on andrographolide content, phenols...
Background: Andrographis paniculata, commonly used in herbal medicine, is known for its hepatoprotective and anti-inflammatory properties. However, limited studies have examined its potential effects on renal and hepatic functions. This study aimed to evaluate the impact of A. paniculata ethanolic leaf extract on renal and hepatic indices in male a...
