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Distinctive carbons of compound 3b

Distinctive carbons of compound 3b

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Reported quinoline-, pyran- and pyranoquinoline-based anticancer and...
Lead Topo II inhibitors, apoptosis inducers, DNA gyrase inhibitors and...
Distinctive carbons of compound 3a
Molecular X-ray structure of compound 3a (displacement parameters are...
+7 Distinctive carbons of compound 3b
Microwave-assisted synthesis and in vitro and in silico studies of pyrano[3,2-c]quinoline-3-carboxylates as dual acting anti-cancer and anti-microbial agents and potential topoisomerase II and DNA-gyrase inhibitors
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  • Jan 2025
A microwave-assisted method was utilized to synthesize novel pyranoquinolone derivatives as dual acting topoisomerase II/DNA gyrase inhibitors with apoptosis induction ability for halting lung cancer and staphylococcal infection. Herein, the designed rationale was directed toward mimicking the structural features of both topoisomerase II and DNA gy...
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