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Detection results of MTB by different diagnostic methods

Detection results of MTB by different diagnostic methods

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Objective: To evaluate the performance of Xpert Mycobacterium tuberculosis (MTB)/rifampicin (RIF) (Xpert MTB/RIF) assay for early diagnosis of pulmonary tuberculosis and detection of rifampicin resistance simultaneously, and compare the efficiency of Xpert MTB/RIF assay, acid-fast bacilli (AFB) smear microscopy and culture techniques Design: Retros...

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... sheet of the results of identification by Xpert/MTB RIF system shows that the isolates were identified as Mycobacterium tuberculosis and sensitive or resistant to RIF. Table 4: Sensitivity and specificity of LJ proportion method of drug susceptibility testing and GeneXpert MTB/ RIF assay for detection of rifampicin resistance PPV: Positive predictive value; NPV: Negative predictive value; LJ: Löwenstein-Jensen; RIF: rifampicin Among the 591 sputum samples which gave valid results, MTB was detected in 78 samples by Xpert/ MTBF assay (Figure 1), and eleven of them were resistant to RIF. The proportion method detected 13 isolates as resistant to RIF, all of which were isoniazid resistant, and hence considered as MDR-TB (Table 4). ...

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