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Decomposition of DTZA at 60°C in pH 8 phosphate buffer where is DTZA control, is copper (400 ng/mL), is glucose (2.8 mg/mL) and is glucose (2.8 mg/mL) with copper (400 ng/mL). 

Decomposition of DTZA at 60°C in pH 8 phosphate buffer where is DTZA control, is copper (400 ng/mL), is glucose (2.8 mg/mL) and is glucose (2.8 mg/mL) with copper (400 ng/mL). 

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Figure 3-Decomposition of DTZA at 60°C in pH 6 phosphate buffer where...
Figure 4-Decomposition of DTZA at 60°C in pH 7 phosphate buffer where...
Figure 5-Decomposition of DTZA at 60°C in pH 8 phosphate buffer where...
The Effect of Glucose and Copper on the Stability of Diatrizoic The Effect of Glucose and Copper on the Stability of Diatrizoic Acid
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  • Jul 2015
Hypaque Sodium Oral Solution is used as a X-ray contrast agent. The active ingredient is diatrizoate sodium. Several bottles of drug product were found to contain elevated levels of inorganic iodide, ranging from 0.001% (w/v) to 0.036% (w/v). The USP specification is no more than 0.02% w/v. The formulation contains sucrose as a sweetener and as a v...
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