Figure 1 - uploaded by Blessy Baby Mathew
Content may be subject to copyright.
Download
View publication
DNA structure and its grooves 

DNA structure and its grooves 

Source publication
Figure 1. DNA structure and its grooves 
Table 1 . DNA alkylating agents [28]
Figure 2. Adsorption of the complex in the DNA grooves [20] 
Table 2 . DNA Cleavage agents
+2 Figure 3. Intercalation of a planar ligand of the complex in the DNA...
KR, S. G., Mathew, B. B., Sudhamani, C. N., & Naik, H. B. (2014). Mechanism of DNA Binding and Cleavage. Biomedicine and Biotechnology, 2(1), 1-9.
Article
Full-text available
  • Jan 2014
The necessity for cellular regulation of DNA led to the development of metallonucleases to catalyze and repair DNA strand breaks. Due to cationic character, three-dimensional structural profiles, and propensity for performing hydrolysis, redox, or photoreactions of metal ions and complexes, have a natural ability for interacting with DNA. Since bin...
Cite
Download full-text

Similar publications

Versatile G-quadruplex-Mediated Strategies in Label-Free Biosensors and Logic Systems
Article
  • Feb 2015
G-quadruplex (G4) as one of significant functional nucleic acids (FNAs) has attracted researchers’ wide attention, and especially has been employed for construction of label-free molecular sensing and logic systems based on the peroxidase-like activity of G4-hemin complex and G4-enhanced luminescence of G4-binding organic dyes. Its cation-dependent...
View
Displacement ellipsoid plot (50 % probability level) of the cationic...
Crystal structure of the adduct 1–CGTACG. a) B‐Type double‐helix units...
Different views of the four‐way‐junction DNA arrangement in the crystal...
Binding site and selected interactions from QM/MM calculations for...
Cell growth inhibition concentrations (IC 50 with 95 %confidence...
Induction of a Four‐Way Junction Structure in the DNA Palindromic Hexanucleotide 5′‐d(CGTACG)‐3′ by a Mononuclear Platinum Complex
Article
Full-text available
  • May 2019
Four‐way junctions (4WJs) are supramolecular DNA assemblies comprising four interacting DNA strands that in biology are involved in DNA‐damage repair. In this study, a new mononuclear platinum(II) complex 1 was prepared that is capable of driving the crystallization of the DNA oligomer 5′‐d(CGTACG)‐3′ specifically into a 4WJ‐like motif. In the crys...
View