Cumulative incidence of organ support and treatment limitations. a Combined mechanical ventilation (MV) and non-invasive ventilation. b Mechanical ventilation (MV). c Vasoactive drugs. d Non-invasive ventilation (NIV). e Treatment limitations. f Renal replacement therapy (RRT)

Cumulative incidence of organ support and treatment limitations. a Combined mechanical ventilation (MV) and non-invasive ventilation. b Mechanical ventilation (MV). c Vasoactive drugs. d Non-invasive ventilation (NIV). e Treatment limitations. f Renal replacement therapy (RRT)

Source publication
Article
Full-text available
Background: The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in patients with COVID-19 is frailty. The degree of frailty could be used to assist both the triage into intensive care, and decisions...

Context in source publication

Context 1
... in vulnerable and 6 days (IQR 3.0-13) in frail patients (p < 0.001). Table 2 shows models revealing the association between frailty and outcome even after controlling for comorbidities and disease severity and treatment strategies. Frailty was associated with increased use of treatment limitations and reduction in respiratory support as shown in Fig. 2 (cumulative incidences in Additional file 9). The use of treatment limitations was significantly higher in frail patients compared to fit patients and vulnerable patients (20-day cumulative incidence was 26% (95% CI 23-29) for fit patients, 40% (33-47) for vulnerable patients and 43% (95% CI 37-48) for frail patients (p < 0.001). The ...

Similar publications

Article
Full-text available
COVID-19 may lead to severe acute respiratory distress syndrome (ARDS) resulting in increased morbidity and mortality. Heart failure and/or pre-existing cardiovascular disease may correlate with poor outcomes and thus require special attention from treating physicians. The present study sought to investigate a possible impact of impaired myocardial...
Preprint
Full-text available
The COVID-19 pandemic has raised several global public health challenges to which the international medical community have responded. Diagnostic testing and the development of vaccines against the SARS-CoV-2 virus have made remarkable progress to date. As the population is now faced with the complex lifestyle and medical decisions that come with li...
Article
Full-text available
Air-Fluidised Care (AFC) is a well known technology, used for the total relief of pressure on tissues by blowing warm air through an amount of small glass spheres (beads). This white paper discusses the history of the development of this 'sand bed' or 'hover bed', as it was named after its development. The current COVID-19 pandemic has resulted in...
Article
Full-text available
Background Critically ill COVID-19 patients have pathophysiological lung features characterized by perfusion abnormalities. However, to date no study has evaluated whether the changes in the distribution of pulmonary gas and blood volume are associated with the severity of gas-exchange impairment and the type of respiratory support (non-invasive ve...
Article
Full-text available
COVID-19 has become unprecedented challenge to ICU management. The measures for containment of the disease and mitigation can be possible only with a proper and organized planning. This study was conducted to evaluate the profile of mechanically ventilated patient in ICU of a Hospital in remote high altitude region during this pandemic.