Correlation of estimated and calculated chloride in fasting serum samples of normal and diabetes mellitus

Correlation of estimated and calculated chloride in fasting serum samples of normal and diabetes mellitus

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Introduction and Aim: The maintenance of fluid balance in the intracellular and extracellular compartmentsis by two major electrolytes, namelysodium and chloride. An increase in sodium is associated with an increase in chloride level and vice versa. The normal reference ranges of sodium and chloride in blood differ by 40mmol/L.On this basis, chlori...

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... determined by the ISE method showed a statistically significant positive correlation with calculated value in both normal and diabetic groups. Further, estimated chloride and calculated chloride values were comparable within the groups in controls and diabetics irrespective of the type of sample (random/fasting) collected, the r value greater than 0.95, p=0.000 in fasting samples of both groups and r = 0.899, p=0.000 in random samples of both groups (Table 2 & 3). The percentage error calculated between estimated chloride and calculated chloride in fasting and random samples of both the groups were negligible (less than 1%), as depicted in table 4 & 5, clearly indicating the accuracy and reliability of the value obtained by using the new simple formula for chloride estimation. ...