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Characteristics of the patients with acute ischemic stroke

Characteristics of the patients with acute ischemic stroke

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Characteristics of the patients with acute ischemic stroke
SBP and DBP values and variability and their association with poor...
Systolic blood pressure variability within 120 hours of admission predicts the functional outcomes at discharge of patients with acute ischemic stroke
Article
Full-text available
  • Apr 2022
Background: Blood pressure variability (BPV) is a predictor of short- and long-term disability in patients with acute ischemic stroke (AIS). Its effect on more immediate functional outcomes has been seldom studied, and the results are inconsistent. We aimed to determine the role of BPV during the first 5 days of hospitalization in functional status...
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... two-tailed P-value < 0.05 was considered statistically significant. Table 1 describes and compares the characteristics of the 134 enrolled patients between outcome groups. The mean age was 75.2 ± 12.9 years, and 71 patients (53.0%) were males. ...

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... 22 [23-25, 27, 29-40, 43, 45, 46, 51-53] articles with available data were analyzed, and the results were combined (OR = 1.11, 95% CI 1.07-1.14). 6 [24,25,31,35,37,38,42,48] studies reported function outcome during hospitalization (range from 3th to 10th days), 11 [23, 27, 30, 32-34, 39, 40, 46, 51, 52] studies reported at 3 months, 2 [45,51] studies reported at both hospitalization time and 3 months, 1 [29] study at 1 month, 1 [36] study at 1 and 3 months, 1 [43] study at 1,3 and 12 months. ...
Blood pressure variability predicts poor outcomes in acute stroke patients without thrombolysis: a systematic review and meta-analysis
Article
Full-text available
  • Nov 2023
  • J NEUROL
Background Stroke is a significant medical condition, and blood pressure stands out as the most prevalent treatable risk factor associated with it. Researches link blood pressure variability (BPV) with stroke; however, the specific relationship between with the outcomes of stroke patients remains unclear. As blood pressure variability and mean blood pressure are interrelated, it remains uncertain whether BPV adds additional information to understanding the outcome of acute stroke patients. Objective To systematically review studies investigating the association between blood pressure variability and prognosis in acute stroke patients. Methods Embase, PubMed, Web of Science, and the Cochrane Library were searched for English language full-text articles from the inception to 1 January 2023. Stroke patients aged ≥ 18 years were included in this analysis. Stroke types were not restricted. Results This meta-analysis shows that higher systolic blood pressure variability is linked to a higher risk of poor outcome, including function disability, mortality, early neurological deterioration, and stroke recurrence, among acute stroke patients without thrombolysis. A higher diastolic blood pressure variability is linked with to a higher risk of mortality and functional disability. Conclusions This review reveals that blood pressure variability is a novel and clinically relevant risk factor for stroke patients’ outcome. Future studies should investigate how best to measure and define BPV in acute stroke. Larger studies are warranted to provide more robust evidence in this area.
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