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Changes in body weight (a), feed intake (b), LDL (c), drink intake (d), cholesterol (e), HDL (f) of different groups of rats.
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Lifestyle associated disorders have always been a hazard for the advancement of chronic diseases. Therefore, use of natural dietary sources is proved to be safe for reducing the occurrence and management of chronic diseases. Okra along with its various parts
has been used for the treatment of several diseases. The present study was done to examine...
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Context 1
... anti-hypercholesterolemic effect of okra seed oil is because of polyunsaturated fatty acids mainly linoleic acid that has the capability to start the relocate of cholesterol in the direction of bile acid. Changes in body weight (a), feed intake (b), LDL (c), drink intake (d), cholesterol (e), HDL (f) of different groups of rats are demonstrated in Figure 1. ...
Context 2
... anti-hypercholesterolemic effect of okra seed oil is because of polyunsaturated fatty acids mainly linoleic acid that has the capability to start the relocate of cholesterol in the direction of bile acid. Changes in body weight (a), feed intake (b), LDL (c), drink intake (d), cholesterol (e), HDL (f) of different groups of rats are demonstrated in Figure 1. ...
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Patients with type 2 diabetes have an increased prevalence of lipid abnormalities. A timely intervention to normalize circulating lipids could reduce the chances of cardiovascular complications. This aim was to evaluate the frequency and pattern of dyslipidemia and effect of age on alteration of lipid profile in male type 2 diabetes. A prospective...
Citations
... Okra is rich in dietary fiber, magnesium, potassium, folic acid,vitamin C, and bioactive components, which has high nutritional value [3]. It is widely used in medicine to prevent cholesterol [4], reduce gastritis, control hypertension and diabetes [5][6][7]. Although the edible part of okra is its tender pod, it is generally believed that okra seed also has high nutritional value. ...
The structure and functional properties of okra seed protein (OSP) were characterized, the ultrasonic homogenization process of OSP nano-emulsion was optimized by response surface methodology (RSM), and its stability was also evaluated in this study. The results suggested that OSP was a high-quality plant protein, rich in glutamic acid. The molecular weight of its main subunits distributed in the range of 10–55 kDa, and some subunits were connected by disulfide bonds. Although the water and oil holding capacities of OSP were inferior to those of soy protein isolate (SPI), its emulsifying ability was superior to that of SPI. And the OSP concentration, ultrasonic time and ultrasonic power had obvious effects on the droplet size of nanoemulsion. The optimum process of OSP emulsion was determined as follows: OSP concentration 2.4 %, ultrasonic power 600 W, ultrasonic time 340 s. Under these conditions, the median droplet size of the nanoemulsion was 192.03 ± 3.48 nm, close to the predicted value (191.195 nm). And the obtained nano-emulsion exhibited high stability to the changes of pH, temperature and ionic strength in the environment. Our results can provide reference for the application of OSP, and promote the development of plant protein-based nanoemulsions.
... The mineral rank of florae is critical not only for the nutritional content of food but also for the development, growth, and yield of crops. Crucial oils derived from several classes (Khan et al., 2020) in this family possess organic roles including physical function (photosynthesis) and environmental purpose (relationships between the flowers and their environment). Furthermore, the chemical structure of the oils from different Satureja strains has been discovered to vary greatly (Slavkovska et al., 2001). ...
This review aims to measure the different aspects of summer savory including biological activity, medicinal properties, nutritional value, food application, prospective health benefits, and its use as an additive in broiler feed. Furthermore, toxicity related to this is also overviewed. Summer savory leaves are abundant in total phenolic compounds (rosmarinic acid and flavonoids) that have a powerful antioxidant impact. Rosmarinic (α-O-caffeoyl-3,4-dihydroxy-phenyl lactic) acid has been identified in summer savory as a main component. According to phytochemical investigations, tannins, volatile oils, sterols, acids, gums, pyrocatechol, phenolic compounds, mucilage, and pyrocatechol are the primary compounds of Satureja species. Summer savory extract shows considerable biological potential in antioxidant, cytotoxic, and antibacterial assays. Regarding antioxidant activity, summer savory extract displays an inhibitory effect on lipid peroxidation. Summer savory also has Fe (III) reductive and free radical scavenging properties and contains minerals and vitamins. Summer savory has important biological properties, including antimicrobial activity and antioxidant activity, and protective effects against Jurkat T Cells, Alzheimer’s disease, cancer, infection, cardiovascular diseases, diabetes, and cholesterol. The leaves and stems of this plant are employed in the food, feed, and pharmacological industries due to their antioxidant properties and substantial nutritional content. Conclusively, summer savory is widely considered beneficial for human health due to its versatile properties and medicinal use.
... Numerous studies have suggested that okra seed oil can decrease cholesterol. Okra seeds are used to create 20-40% of the world's oil (5,6). ...
The food industry generates a diverse range of waste byproducts during fruit processing, which can be repurposed to create functional foods and other valuable commodities. In this particular study, leftover agro-waste from pomegranate juice was valorized to obtain pomegranate seed oil (PSO), while utilizing sunflower oilseed cake to produce sunflower meal protein concentrate (SMPC). These two extracted components were then combined as ingredients to produce High Nutria Omega 5 (HNO5) cookies. To ensure the quality and viability of pomegranate seed oil, a comprehensive set of laboratory analytical procedures were employed to evaluate its characteristics. Subsequently, different ratios of pomegranate seed oil and sunflower meal protein concentrate were utilized to develop the HNO5 cookie products. These cookies underwent thorough sensory, physicochemical, storage, and proximate evaluations as well as efficacy studies to assess their overall nutritional quality and shelf-life properties. As compared to the control feed, the findings of the renal and liver functional tests indicated a favorable effect on ALT, AST, ALP, serum urea, creatinine, albumin, globulins, total proteins, and A/G ratio. The results revealed that PSO and SMPC cookies containing 15% PSO and 15% SMPC exhibited stability in numerous physicochemical and sensory assessments. The punicic acid in HNO5 cookies significantly reduced the effects of starvation in rats and progressively improved several metabolic processes and overall health profiles.
Graphical Abstract
... At the same time, linolenic acid as essential fatty acids, is only through food intake for the normal growth and development of the human body (Rincón-Cervera et al., 2016). Linolenic acid can be used in the body to promote fat metabolism, composition of body cells, synthesis of prostaglandins and related to vision, brain and other aspects of behavioral development (Khan et al., 2020;Bourourou et al., 2016). In our previous study, we analyzed and identified the volatile compounds produced during the heating process of oleic and linoleic acids, and found that these two fatty acids produced a large number of volatile substances during heating, such as volatile aldehydes, alcohols, ketones, acids and furans (Bao et al., 2022). ...
Abstract Linolenic acid is an important fatty acid, and volatiles generated by its oxidation are the major components of food flavor. In this study, volatile components generated from linolenic acid during heating were detected and analyzed by using thermal desorption cryo-trapping system coupled with gas chromatography-mass spectrometry. A total of 52 volatile compounds were identified, including aldehydes (18), ketones (12), alcohols (6), furans (4), acids (6) and aromatic compounds (6). The forming temperature of each volatile compound was also determined. It was found that most volatile compounds with shorter carbon chains were mainly generated at lower temperatures, while volatile compounds with longer carbon chains were mainly produced at higher temperatures. Results of principal component analysis show that most of the identified volatiles were considered as the characteristic ones of the high temperature points. Potential thermal oxidation mechanism of linolenic acid was also given at the same time.
... [124] Scientific studies have shown that compounds present in A. esculentus seed oil induce potential beneficial effects on human health, such as the prevention of chronic diseases. [125,126] Gemede [125] and Gemede [127] when determining the molar ratios and the bioavailability of A. esculentus consumed by indigenous Ethiopians, identified in the composition of the seeds a large amount of high quality proteins, presenting essential amino acids of great importance when compared to others vegetable protein sources. A. esculentus seeds are a source of carbohydrates, dietary fiber and minerals, such as potassium, phosphorus, magnesium, calcium and iron; [125] are high in Vitamin E, a powerful natural antioxidant, of great nutritional importance and potential for improving human health. ...
... [229] In addition, unlike most dietary components that inhibit cholesterol absorption, such as phytosterols and soluble fiber, stearic acid has good tissue absorption. [230] The study carried out by Khan, [126] with the oil from the seeds of A. esculentus, demonstrated a significant effect in the reduction of triglycerides, LDL, however, observed the increase of HDL in the test carried out with animals. This anti-hypercholesterolemic effect is based precisely on the ability of fatty acids, such as stearic acid and linoleic acid, to reallocate cholesterol towards bile acid. ...
... When regularly consumed at an effective level in a variety of diets, they not only provide basic nutrition to the human body, but also have a potential positive impact on human health (Granato et al., 2020). Now common functional foods include probiotics (Long et al., 2022), active factors from natural sources (Khan et al., 2021;Jiang et al., 2021), foods composed of clear compound nutrients (Califa-Estwick et al., 2021;ur Rehman et al., 2021), etc. As a new source of food from a research perspective, P. praeruptorum Dunn may play a role in Practical Application: Peucedanum praeruptorum Dunn is a kind of natural plant. ...
Abstract Peucedanum praeruptorum Dunn is a natural plant with expectorant, antitussive, anti-asthmatic, anti-inflammatory, antispasmodic and sedative effects. It is used in traditional Chinese medicine. The key active substances extracted after separation are also used to process functional food. Recent advances in the development of Peucedanum praeruptorum Dunn industrially have increased the market demand. In particular, the study of the physiological activity of P. praeruptorum Dunn has always been a research hotspot; however, limited data exist currently. This study reviews the research developments associated with the physiological activities of P. praeruptorum Dunn in terms of cardiovascular, expectorant and antitussive, antitumor, and anti-inflammatory effects. The results serve as a standard of reference for further investigation into the pharmacologic role of Peucedanum praeruptorum Dunn.
... Furthermore, Liao et al. and Chen et al. indicated that supplementation of okra polysaccharides could elevate HDL-C concentration in HFD-STZ-induced diabetic rats and KKAy mice, as well (Chen, 2019;Liao et al., 2019). Also, another in vivo study demonstrated that a diet containing 6%, 12%, and 18% of okra seed oil had a beneficial effect on HDL-C level in Hypercholesterolemic rats (Khan et al., 2021). In addition, supplementation with 100, 200, and 300 mg/kg of whole okra, okra seed, and okra peel could significantly increase HDL-C levels in diabetic rats (Yaradua et al., 2017). ...
Diabetes mellitus (DM) is a prevalent endocrine disorder with clinical manifestations of hyperglycemia and hyperlipidemia due to malfunction and/ or insufficiency of insulin in the body. DM is considered as a public health problem worldwide due to its adverse effects on the body. Okra (Abelmoschus esculentus L.) is an annual medicinal plant rich in antioxidant components, bioactive polysaccharides, and fibers. This systematic review aimed to summarize the effects of okra on glycemic indices and lipid profile. PubMed, Scopus, Web of Knowledge, and Google scholar databases were searched until May 2021 with no limitation. Totally, 54 studies which investigated the effects of okra on glycemic control and lipid profile were included in the present systematic review. Most of the included studies showing favorable effects of okra products on glycemic variables and lipid profile, were performed on animal models. Therefore, more clinical trials are needed for a definitive conclusion.
Left ventricular hypertrophy (LVH), a complex cardiac condition characterized by the enlargement and thickening of the left ventricle, is primarily associated with hypertension and valvular heart disease. Recent studies have identified familial hypercholesterolemia (FH) as a secondary cause of LVH. It is characterized by high low-density lipoprotein cholesterol (LDL-C) in blood. FH is an inherited disorder which involves genetic variations associated with abnormal metabolism of LDL-C. This review article aims to provide a comprehensive overview of the relationship between FH and LVH. It summarizes the current understanding of the pathophysiological mechanisms underlying this association and discusses its implications for clinical practice. Elevated LDL-C levels in FH patients lead to accelerated atherosclerosis and an increased risk of premature cardiovascular events. Animal models and clinical observations provide insights into the mechanistic links between elevated LDL-C levels, oxidative stress, inflammation, and LVH development. Early diagnosis of FH would certainly play a critical role in preventing or delaying the development of LVH and subsequent cardiovascular complications. Preemptive measures emphasize the identification of at risk individuals, in-depth clinical evaluations, and implementation of effective treatments including lifestyle modifications, statins, and adjunctive therapies, such as PCSK9 inhibitors or lipoprotein apheresis. By increasing the awareness of FH as a secondary cause of LVH, healthcare professionals can improve early detection and implement appropriate management strategies to mitigate the cardiovascular burden associated with this inherited disorder.
