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Sleep is a fundamental physiological process that not only supports immune function but also contributes significantly to overall well-being. Because of the established decline in the average amount of sleep due to lifestyle and rise in shift work over the past few decades, exploring the relationship between sleep and immunity has become crucial. M...
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... chloride ions (Cl -) to enter the neuron. This influx of chloride hyperpolarizes the neuron's membrane potential, lowering the likelihood of action potentials and ultimately inhibiting neurotransmission [59] . Furthermore, certain drugs like benzodiazepines can bind to the GABAA receptor at an allosteric site, enhancing its affinity for GABA (Fig. 3). This potentiation of GABA's inhibitory effect contributes to the relaxation and sedative properties associated with benzodiazepine use. Interestingly, while the brain contains five wake-promoting transmitters, GABA stands as the sole neurotransmitter that actively promotes sleep. Its role in inhibiting neural activity plays a vital ...
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... Zinc has been shown to increase sleep quality, particularly when paired with magnesium. Though both Chamomile Flower (0.96 %) and Passion flower (0.81 %) contain minor levels of zinc, their presence may nonetheless contribute to sleep regulation, although indirectly (Paliwal & Ambwani, 2024). The purpose of this study was to assess the efficacy of Chamomile flower and Passion flower as therapies for primary insomnia using the Pittsburgh Sleep Quality Index (PSQI). ...
Primary insomnia, a sleep disorder characterized by difficulty falling or staying asleep, can negatively impact overall health. This study explores the effect of chamomile and passionflower on sleep quality, stress, melatonin production, and liver function in individuals with primary insomnia. A total of 90 participants, aged 25-45, were selected using the Pittsburgh Sleep Quality Index (PSQI) and divided into three groups: control, chamomile powder 1g/day tea, and passionflower powder 1g/day tea for 8 weeks. Results showed that chamomile significantly alleviated insomnia symptoms compared to passionflower. Chamomile also led to reductions in daytime dysfunction and salivary cortisol levels, indicating stress reduction, while passionflower showed no significant changes in cortisol. Both herbs positively impacted liver enzymes. The findings indicate that chamomile is more effective than passionflower in improving sleep quality, reducing stress, boosting melatonin production, and enhancing liver function in individuals with insomnia, making it a more beneficial treatment for primary insomnia.
