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Antibacterial activity of the AXOTL-13 peptide on Staphylococcus aureus. (a) Viability percentage after 20 h of growth (endpoint). (b) Viability percentage every hour for 20 h (growth kinetics). C− (N/T): bacteria without treatment. C+ (NaClO): bacteria treated with 0.06% NaClO. C+ (Ramosin): bacteria treated with 40 μM Ramosin peptide. Kinetics data are presented as mean ± SD and endpoint as mean ± SEM. ns: p ≥ 0.005. **: p < 0.01. Blue asterisk: comparison with NaClO; red asterisk: comparison with Ramosin.

Antibacterial activity of the AXOTL-13 peptide on Staphylococcus aureus. (a) Viability percentage after 20 h of growth (endpoint). (b) Viability percentage every hour for 20 h (growth kinetics). C− (N/T): bacteria without treatment. C+ (NaClO): bacteria treated with 0.06% NaClO. C+ (Ramosin): bacteria treated with 40 μM Ramosin peptide. Kinetics data are presented as mean ± SD and endpoint as mean ± SEM. ns: p ≥ 0.005. **: p < 0.01. Blue asterisk: comparison with NaClO; red asterisk: comparison with Ramosin.

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Background/Objectives: Antimicrobial peptides are essential molecules in the innate immunity of various organisms and possess a broad spectrum of antimicrobial, antitumor, and immunomodulatory activities. Due to their multifunctionality, they are seen as an alternative for controlling bacterial infections. Although conventional antibiotics have imp...