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Analysis workflow. Figure illustrates the most important steps of the analysis process. Optic radiation is shown as an example of a

Analysis workflow. Figure illustrates the most important steps of the analysis process. Optic radiation is shown as an example of a

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Multiple sclerosis and aquaporin-4 antibody neuromyelitis optica spectrum disorders are distinct autoimmune CNS disorders with overlapping clinical features but differing pathology. Multiple sclerosis is primarily a demyelinating disease with the presence of widespread axonal damage, while neuromyelitis optica spectrum disorders is characterized by...

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... enabled dipole inversion algorithm 39 was used for unwrapping phase data and estimating susceptibility maps with the cerebrospinal fluid used for value referencing. The QSM images were visually inspected for PRLs and cross referenced with corresponding FLAIR images ( Supplementary Fig. 1). ...
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... used to study the relationship between lesion count (PRLs, cortical lesions) and NDI in individual tracts. For all hypotheses containing multiple comparisons (multiple tracts or cortical regions), the familywise error was controlled for with Benjamini-Hochberg correction (P = 0.05). To visualize the analysis workflow, we present the process in Fig. ...