- Full Neutralization of Centruroides sculpturatus Scorpion Venom by Combining Two Human Antibody Fragments

Alignment of the sequences of the toxins neutralized by scFvs LR and 10FG2 and the main toxins of C. sculpturatus venom (CsEd and CsEM1a in bold). Cn2, C. noxius toxin 2; Css2 and Css4, C. suffusus toxins 2 and 4; CsEd and CsEM1a, C. sculpturatus toxins; Ct1a, C. tecomanus toxin 1; CeII9, C. elegans toxin 2; Cll1 and Cll2, C. limpidus toxins 1 and 2. ɑ, neutralizing scFv [11,12]. Dots indicate that these residues are conserved with respect to Cn2 toxin.

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Reference

Full Neutralization of Centruroides sculpturatus Scorpion Venom by Combining Two Human Antibody Fragments - Scientific Figure on ResearchGate. Available from: https://www.researchgate.net/figure/Alignment-of-the-sequences-of-the-toxins-neutralized-by-scFvs-LR-and-10FG2-and-the-main_fig1_355298645 [accessed 13 Jun 2025]

Caption

Alignment of the sequences of the toxins neutralized by scFvs LR and 10FG2 and the main toxins of C. sculpturatus venom (CsEd and CsEM1a in bold). Cn2, C. noxius toxin 2; Css2 and Css4, C. suffusus toxins 2 and 4; CsEd and CsEM1a, C. sculpturatus toxins; Ct1a, C. tecomanus toxin 1; CeII9, C. elegans toxin 2; Cll1 and Cll2, C. limpidus toxins 1 and 2. ɑ, neutralizing scFv [11,12]. Dots indicate that these residues are conserved with respect to Cn2 toxin.

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<a href="https://www.researchgate.net/figure/Alignment-of-the-sequences-of-the-toxins-neutralized-by-scFvs-LR-and-10FG2-and-the-main_fig1_355298645"><img src="https://www.researchgate.net/publication/355298645/figure/fig1/AS:11431281420581072@1746256446828/Alignment-of-the-sequences-of-the-toxins-neutralized-by-scFvs-LR-and-10FG2-and-the-main.tif" alt="Alignment of the sequences of the toxins neutralized by scFvs LR and 10FG2 and the main toxins of C. sculpturatus venom (CsEd and CsEM1a in bold). Cn2, C. noxius toxin 2; Css2 and Css4, C. suffusus toxins 2 and 4; CsEd and CsEM1a, C. sculpturatus toxins; Ct1a, C. tecomanus toxin 1; CeII9, C. elegans toxin 2; Cll1 and Cll2, C. limpidus toxins 1 and 2. ɑ, neutralizing scFv [11,12]. Dots indicate that these residues are conserved with respect to Cn2 toxin."/></a>