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Algorithm for the treatment of hypertension. A: ACE inhibitors or ARBs, B:β-blocker, C: calcium channel blocker, D: diuretics. ACE: angiotensin-converting enzyme, ARBs: angiotensin-receptor blockers.

Algorithm for the treatment of hypertension. A: ACE inhibitors or ARBs, B:β-blocker, C: calcium channel blocker, D: diuretics. ACE: angiotensin-converting enzyme, ARBs: angiotensin-receptor blockers.

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The risk attributable to cardiovascular disease (CVD) that is induced by hypertension in the Korean population is 35% for stroke and 21% for ischemic heart disease. The prevalence of hypertension in persons older than 30 years is as high as 34.4% in men and 26.5% in women, and the prevalence of prehypertension is 39.4% in men and 30.6% in women. Th...

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... β-blockers) are recommended for patients who are younger than 55. CCBs or diuretics are more effec- tive first line agents for the patients aged 55 or older. 13) If the BP is still insufficiently controlled with one drug, the combination of A(or B)+C or D is recommended by adding a different class drug, and then A(or B)+ C+D is added if necessary (Fig. 1). The selection of drugs for high-risk conditions is based on the favorable outcome data from the reported clinical trials. In case of diabetes or renal disease, ACE inhibitors are recom- mended as an initial drug, ACE inhibitors and diuretics are appropriate for heart failure patients, thiazide-type diuretics and long-acting CCBs are ...

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... For example, 120-139/80-89 mm Hg range is termed 'prehypertension' in Korea and Taiwan, 'normal high BP' in China, and defines both 'normal BP' and 'high-normal BP' in Japan. 9,92,[96][97][98] The current Japanese hypertension guidelines recommend a BP target of o150/90 mm Hg for elderly patients aged ⩾ 75 years, whereas in the Chinese guidelines, the same BP target is recommended for elderly patients aged ⩾ 65 years. 92,98 Local guidelines give limited guidance specifically on the management of systolic hypertension, although some experts acknowledge its higher prevalence in the elderly population. ...
... 98 Antihypertensive treatment is recommended in elderly patients but it is advised that BP reduction should be more gradual in this patient population. 9,[96][97][98] The Japanese and Taiwanese guidelines recognize that lowering elevated SBP is important even in patients who have low DBP. 9,98 However, the Japanese guidelines recommend that in the presence of coronary artery disease, changes in DBP be monitored while lowering SBP to the target level. ...
... The primary goal of antihypertensive treatment is to lower BP, thereby reducing cardiovascular complications. 9,97,98 Non-pharmacological interventions for BP control recommended by Asian guidelines focus on lifestyle modifications, primarily reducing dietary sodium, weight loss, adopting a diet rich in fruit/vegetables and low-fat dairy products, physical activity, smoking cessation, and reducing alcohol intake. 9,96-98 However, few patients achieve BP goals through lifestyle modifications alone and antihypertensive drug therapy is generally required. ...
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